Emerg Infect Dis. 2022 Apr;28(4):903-905. doi: 10.3201/eid2804.211433.
We describe an immunosuppressed patient with bacteremia and pneumonia caused by Legionella pneumophila subspecies fraseri in China. We confirmed this diagnosis by using nanopore sequencing of positive blood cultures and subsequent recovery from buffered-charcoal yeast extract culture. Nanopore sequencing is an effective tool for early diagnosis of atypical infections.
我们描述了一例中国免疫抑制患者发生嗜肺军团菌弗雷泽亚种菌血症和肺炎。我们通过对阳性血培养物进行纳米孔测序,并随后从缓冲炭酵母提取物培养物中恢复,从而确认了这一诊断。纳米孔测序是早期诊断非典型感染的有效工具。