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在初级保健环境中针对心血管疾病高危人群的身体训练计划:一项随机临床试验。

Physical training program for people at risk of cardiovascular disorders in the primary care setting: A randomized clinical trial.

机构信息

Rehabilitation Department, Hospital Universitari Mútua Terrassa, University of Barcelona, Terrassa 08221, Barcelona, Spain.

Research Unit, Fundació Docència i Recerca Mútua Terrassa, University of Barcelona, Terrassa 08221, Barcelona, Spain.

出版信息

Med Clin (Barc). 2022 Nov 25;159(10):475-482. doi: 10.1016/j.medcli.2022.01.020. Epub 2022 Mar 19.

DOI:10.1016/j.medcli.2022.01.020
PMID:35318946
Abstract

BACKGROUND AND OBJECTIVE

The impact of a physical training program on moderate-vigorous physical activity is still poorly known in primary cardiovascular prevention. Our objective was to determine the efficacy of a physical training program to promote moderate-vigorous physical activity and exercise in individuals at risk of suffering a cardiovascular event.

PATIENTS AND METHODS

Randomized, parallel group controlled trial performed from October 2014 to July 2016. Sedentary patients at risk of suffering a cardiovascular event were randomized to the control group (CG) (72) or the intervention group (IG) (75). Intervention consisted of a 2-month physical training program. The main outcome was the proportion of patients achieving a "relevant response to Physical Activity" (increase≥240METs-min/week in moderate-vigorous Physical Activity using the International Physical Activity Questionnaire (IPAQ)). Secondary outcomes included the proportion of patients performing an "adequate amount of exercise" (≥360METs-min/week in moderate-vigorous exercise using the IPAQ).

RESULTS

Of the 147 patients randomized, 132 (90%) completed the follow-up. Adherence to exercise performance was 91% and no adverse effects were recorded. The proportion of patients in the IG versus CG achieving the main outcome was 34.9% vs 11.6%; OR [95%CI]: 4.2 [1.7-10.4]. Furthermore, more patients in the IG performed an adequate amount of exercise (33.3% vs. 11.6%; OR: 4.1 [1.6-10.5]).

CONCLUSION

A short-duration physical training program performed in the primary care setting is efficacious and safe in promoting moderate-vigorous physical activity and exercise in the short-term, in a population at risk of suffering a cardiovascular event.

TRIAL REGISTRATION

"Training Programme in Physical Activity". NCT03717363.

TRIAL REGISTRATION

Clinicaltrials.gov.

摘要

背景与目的

在初级心血管预防中,体力训练计划对适度剧烈体力活动的影响仍知之甚少。我们的目的是确定体力训练计划在有发生心血管事件风险的个体中促进适度剧烈体力活动和运动的效果。

患者与方法

这是一项从 2014 年 10 月至 2016 年 7 月进行的随机、平行组对照试验。有发生心血管事件风险的久坐患者被随机分为对照组(CG)(72 例)或干预组(IG)(75 例)。干预措施包括为期 2 个月的体能训练计划。主要结局是评估患者实现“体力活动的相关反应”(使用国际体力活动问卷(IPAQ),每周中度至剧烈体力活动增加≥240METs-min)的比例。次要结局包括评估患者实现“足够运动量”(使用 IPAQ,每周中至剧烈运动≥360METs-min)的比例。

结果

在随机分组的 147 例患者中,有 132 例(90%)完成了随访。运动表现的依从率为 91%,未记录到不良反应。IG 组与 CG 组达到主要结局的患者比例分别为 34.9%和 11.6%;比值比[95%置信区间]:4.2[1.7-10.4]。此外,IG 组有更多的患者进行了足够的运动(33.3%比 11.6%;比值比:4.1[1.6-10.5])。

结论

在初级保健环境中进行的短期体能训练计划在促进有发生心血管事件风险的人群中在短期内进行中度至剧烈体力活动和运动是有效和安全的。

试验注册

“体力活动训练计划”。NCT03717363。

试验注册

Clinicaltrials.gov。

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