Department of Orthopaedic Surgery, Johns Hopkins Hospital, Baltimore, Maryland.
Johns Hopkins School of Medicine, Baltimore, Maryland.
JBJS Case Connect. 2022 Mar 23;12(1):01709767-202203000-00076. doi: e22.00052.
We present the case of an 81-year-old woman who developed profound hypercalcemia requiring admission to the intensive care unit after calcium sulfate bead use during revision hip arthroplasty. The patient's serum calcium level peaked at 21.0 mg/dL and was associated with acute encephalopathy. After treatment with calcitonin and bisphosphonates, her serum calcium level normalized and her mentation improved.
The risk of clinically significant hypercalcemia should be considered when using calcium sulfate during orthopaedic surgery.
我们报告了一例 81 岁女性病例,该患者在revision hip arthroplasty(髋关节翻修术)中使用硫酸钙珠后出现严重高钙血症,需要入住重症监护病房。患者血清钙水平最高达 21.0mg/dL,并伴有急性脑病。经降钙素和双膦酸盐治疗后,其血清钙水平恢复正常,神志改善。
在骨科手术中使用硫酸钙时应考虑发生临床显著高钙血症的风险。