卡拉奇一家三级护理医院的法裔美国-英国急性髓系白血病亚型的频率。

Frequency of French-American-British subtypes of acute myeloid leukaemia in a tertiary care hospital of Karachi.

机构信息

Department of Oncology, Jinnah Postgraduate Medical Centre, Karachi, Pakistan.

Department of Oncology, Jinnah Postgraduate Medical Centre, Karachi.

出版信息

J Pak Med Assoc. 2022 Mar;72(3):537-539. doi: 10.47391/JPMA.1490.

DOI:10.47391/JPMA.1490

PMID:35320239

Abstract

The aim of this study was to determine the frequency of different subtypes of acute myeloid leukaemia (AML) cases that presented in a tertiary care hospital of Karachi. It was a retrospective cross-sectional study, conducted in the hospital's Oncology department. Data of patients admitted during 2018 was collected from the records. In this study, patients were included using the non-probable convenient sampling technique. Selected cases were classified according to the French-American-British (FAB) classification and data analysis was performed using the SPSS version 25.0. Among the 61 patients included in the study, 28 were males and 33 were females, with a male to female ratio of 1:1.2. The patients' age ranged between 15 and 92 years and the mean age of diagnosis was 36.13± 15.5 years. M2 was the most common FAB subtype in 14(29.8%) patients, followed by M1 in 11(23.4%) patients. Myeloperoxidase (MPO) was positive in 44 (71.4%) of those cases.

摘要

本研究旨在确定在卡拉奇的一家三级护理医院中出现的不同亚型急性髓系白血病（AML）病例的频率。这是一项回顾性的横断面研究，在医院的肿瘤科进行。2018 年期间住院患者的数据从记录中收集。在这项研究中，使用非概率方便抽样技术纳入患者。根据法国-美国-英国（FAB）分类对选定的病例进行分类，并使用 SPSS 版本 25.0 进行数据分析。在纳入研究的 61 名患者中，28 名男性和 33 名女性，男女比例为 1:1.2。患者年龄在 15 至 92 岁之间，诊断时的平均年龄为 36.13±15.5 岁。在 14 名（29.8%）患者中，最常见的 FAB 亚型为 M2，其次为 M1（11 例，占 23.4%）。在这些病例中，有 44 例（71.4%）髓过氧化物酶（MPO）阳性。