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[卒中重症监护病房管理的最新进展]

[Update on Intensive Care Unit Management of Stroke].

作者信息

Salih Farid, Becker Alexandra, Andrees Nicolai, Tempel Hannah

出版信息

Anasthesiol Intensivmed Notfallmed Schmerzther. 2022 Mar;57(3):222-229. doi: 10.1055/a-1374-1932. Epub 2022 Mar 23.

Abstract

In this review, we provide an update on the intensive care unit (ICU) management of ischemic stroke. Over the last decade, new evidence has led to rapid changes in the early management of patients admitted with acute ischemic stroke. Nevertheless, stroke remains a leading cause of disability. Consequently, a significant number of patients with acute ischemic stroke require ICU level care. The most frequent reasons for ICU admissions are large infarction with potential swelling, reduced level of consciousness, secondary hemorrhagic transformation, acute symptomatic seizures or respiratory failure and stroke-related disorders of the brain-heart interaction. Moreover, there is an increasing number of patients receiving intravenous thrombolysis or mechanical thrombectomy with a subsequent need of ICU monitoring. Several studies have shown that the implementation of specialized neuro-intensive care teams help to improve functional outcome after acute ischemic stroke. The main goal in the ICU management of stroke patients is to prevent secondary brain injury. To this end, a comprehensive approach to optimize systemic physiological homeostasis, control intracranial pressure, cerebral perfusion, hemodynamic and respiratory parameters is needed. Here, we summarize recent advances in invasive and non-invasive neuro-monitoring, decision making in decompressive neurosurgery for large supratentorial or cerebellar infarction, specific cardiorespiratory management, nutrition, temperature management and mobilization strategies in ischemic stroke.

摘要

在本综述中,我们提供了关于缺血性中风重症监护病房(ICU)管理的最新情况。在过去十年中,新的证据促使急性缺血性中风患者早期管理发生了迅速变化。然而,中风仍然是导致残疾的主要原因。因此,相当数量的急性缺血性中风患者需要ICU级别的护理。入住ICU最常见的原因是大面积梗死伴潜在肿胀、意识水平降低、继发性出血转化、急性症状性癫痫发作或呼吸衰竭以及与中风相关的脑心相互作用障碍。此外,越来越多的患者接受静脉溶栓或机械取栓治疗,随后需要ICU监测。多项研究表明,实施专业的神经重症监护团队有助于改善急性缺血性中风后的功能结局。中风患者ICU管理的主要目标是预防继发性脑损伤。为此目的,需要一种综合方法来优化全身生理稳态、控制颅内压、脑灌注、血流动力学和呼吸参数。在此,我们总结了缺血性中风在有创和无创神经监测、大脑半球或小脑大面积梗死减压性神经外科手术决策、特定心肺管理、营养、体温管理和动员策略方面的最新进展。

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