Augenzentrum am St. Franziskus Hospital, Münster, Deutschland.
Department für Augenheilkunde, Universitätsklinikum Tübingen, Deutschland.
Klin Monbl Augenheilkd. 2022 May;239(5):676-685. doi: 10.1055/a-1686-5158. Epub 2022 Mar 23.
Case report based presentation of the current German interdisciplinary guideline on the diagnosis and management of juvenile idiopathic arthritis-associated (JIA) uveitis.
Guideline of the German Society of Ophthalmology, the Society of Paediatric and Adolescent Rheumatology, the German Society of Rheumatology, the Professional Association of German Ophthalmologists, with the participation of patient representatives. Recent primary publications were critically graduated for evidence and recommendations; the methodology included consensus building through Delphi rounds and external peer review. The outcomes are presented with typical case studies.
Once JIA is first diagnosed, periodic ophthalmological check-ups should promptly be instituted ensuring that uveitis is diagnosed before irreversible sequelae become manifest. High-quality patient care can be provided depending on the severity of each uveitis case. At present, anti-inflammatory treatment relies on corticosteroids, conventional synthetic (cs), biological (b) and other disease-modifying anti-rheumatic drugs (DMARDs).
Timely diagnosis and state-of-the-art guideline-based management can significantly improve the long-term outcome of JIA-associated uveitis.
基于病例报告,介绍目前德国跨学科的幼年特发性关节炎相关性(JIA)葡萄膜炎诊断和管理指南。
德国眼科学会、儿科和青少年风湿病学会、德国风湿病学会、德国眼科医生专业协会的指南,有患者代表参与。对近期的主要出版物进行了严格的分级,以评估证据和建议的质量;方法包括通过德尔菲(Delphi)轮次和外部同行评审来达成共识。结果以典型病例研究的形式呈现。
一旦首次诊断出 JIA,应立即进行定期眼科检查,确保在不可逆转的后遗症出现之前诊断出葡萄膜炎。根据每个葡萄膜炎病例的严重程度,可以提供高质量的患者护理。目前,抗炎治疗依赖于皮质类固醇、传统合成(cs)、生物(b)和其他疾病修饰抗风湿药物(DMARDs)。
及时的诊断和基于最新指南的管理可以显著改善 JIA 相关性葡萄膜炎的长期预后。