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尼日利亚拉各斯感染与未感染艾滋病毒的青春期女孩的生长发育和青春期发育:一项比较横断面研究。

Growth and Pubertal Development Among HIV Infected and Uninfected Adolescent Girls in Lagos, Nigeria: A Comparative Cross-Sectional Study.

作者信息

Agatha David, Titilola Gbaja-Biamila, Abideen Salako, Oluwatosin Odubela, Agatha Wapmuk, Sabdat Ekama, Tomilola Musari-Martins, Priscilla Ezemelue, Ebiere Herbertson, Oliver Ezechi

机构信息

Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.

出版信息

Glob Pediatr Health. 2022 Mar 19;9:2333794X221082784. doi: 10.1177/2333794X221082784. eCollection 2022.

Abstract

This study aimed to compare growth and pubertal developmental parameters among HIV-infected and uninfected adolescent girls (11-19 years) in Lagos using a cross-sectional approach. Height, weight, BMI -scores, sexual maturity rating by Tanner stages and age at menarche, were compared in the 2 groups. The mean age was similar in both groups (13.2 [±2.3] years and 13.6 [±1.6] years for HIV positive and negative respectively [ = .13]). Majority (66.2%) were in Junior Secondary classes and the mean socioeconomic class was 2.5 (±0.9). HIV-infected girls had significantly lower height, weight, and BMI scores compared to their uninfected counterparts. The proportion that had attained Tanner stages 3 to 5 were significantly lower among the HIV-positive participants. The study identified lower growth parameters and pubertal delay among HIV-infected adolescent females compared to HIV uninfected girls. Growth and sexual maturation assessment should form part of routine care of adolescents living with HIV.

摘要

本研究旨在采用横断面研究方法,比较拉各斯地区感染和未感染艾滋病毒的11至19岁青春期女孩的生长发育和青春期发育参数。比较两组的身高、体重、体重指数评分、坦纳分期的性成熟评级和初潮年龄。两组的平均年龄相似(艾滋病毒阳性组为13.2[±2.3]岁,阴性组为13.6[±1.6]岁,P = 0.13)。大多数(66.2%)在初中班级,平均社会经济阶层为2.5(±0.9)。与未感染艾滋病毒的女孩相比,感染艾滋病毒的女孩的身高、体重和体重指数评分显著更低。在艾滋病毒阳性参与者中,达到坦纳3至5期的比例显著更低。该研究发现,与未感染艾滋病毒的女孩相比,感染艾滋病毒的青春期女性的生长参数更低且青春期延迟。生长和性成熟评估应成为艾滋病毒感染青少年常规护理的一部分。

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