Pace Annalisa, Milani Alessandro, Rossetti Valeria, Iannella Giannicola, Maniaci Antonino, Cocuzza Salvatore, Alunni Fegatelli Danilo, Vestri Annarita, Magliulo Giuseppe
Organi di Senso Department, Sapienza University, Rome, Italy.
Scienze Chirurgiche Department, Sapienza University, Rome, Italy.
Nat Sci Sleep. 2022 Mar 17;14:475-482. doi: 10.2147/NSS.S346241. eCollection 2022.
Obstructive sleep apnoea (OSA) is a common disease with significantly related complications. Since a connection between the vestibular nucleus and sleep regulator pathways has been demonstrated, vestibular evaluation in OSA patients was partially studied and none used functional head impulse test (fHIT) for this purpose. This paper aimed at evaluating the vestibular function in patients affected by OSA using fHIT, selecting patients who did not present any other related to cardiovascular, neurological, or metabolic diseases.
Patients enrolled had a diagnosis of OSA by polysomnography type III and were cataloged according to American Association of Sleep Medicine criteria. Each patient underwent fHIT. Statistical significance was set at 0.05.
A total of 85 patients were enrolled in the study of which 50 had a diagnosis of OSA and were included in the case group, while 35 belonged to the control group. In 88.6% of subjects of the case group was evidenced a vestibular impairment with a substantial difference between the two study groups (p<0.05).
The results show that the incidence of vestibular lesions in patients with obstructive sleep apnoea is underestimated and that fHIT can identify these lesions early.
阻塞性睡眠呼吸暂停（OSA）是一种常见疾病，伴有显著相关并发症。由于前庭核与睡眠调节通路之间的联系已得到证实，因此对OSA患者的前庭评估进行了部分研究，但均未使用功能性头部脉冲试验（fHIT）进行此项评估。本文旨在使用fHIT评估OSA患者的前庭功能，选择未患有任何其他心血管、神经或代谢相关疾病的患者。
纳入的患者通过Ⅲ型多导睡眠图诊断为OSA，并根据美国睡眠医学协会标准进行分类。每位患者均接受fHIT检查。统计学显著性设定为0.05。
共有85名患者参与本研究，其中50名诊断为OSA并纳入病例组，35名属于对照组。病例组88.6%的受试者存在前庭功能损害，两个研究组之间存在显著差异（p<0.05）。
结果表明，阻塞性睡眠呼吸暂停患者前庭病变的发生率被低估，且fHIT可早期识别这些病变。
