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Presence of the narrow-spectrum OXA-1 β-lactamase enzyme is associated with elevated piperacillin/tazobactam MIC values among ESBL-producing clinical isolates (CANWARD, 2007-18).

作者信息

Walkty A, Karlowsky J A, Lagacé-Wiens P R S, Golden A R, Baxter M R, Denisuik A J, McCracken M, Mulvey M R, Adam H J, Zhanel G G

机构信息

Department of Medical Microbiology and Infectious Diseases, Max Rady College of Medicine, University of Manitoba, Winnipeg, Canada.

Shared Health, Winnipeg, Canada.

出版信息

JAC Antimicrob Resist. 2022 Mar 21;4(2):dlac027. doi: 10.1093/jacamr/dlac027. eCollection 2022 Apr.

DOI:10.1093/jacamr/dlac027
PMID:35321395
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8935204/
Abstract
摘要

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Presence of the narrow-spectrum OXA-1 β-lactamase enzyme is associated with elevated piperacillin/tazobactam MIC values among ESBL-producing clinical isolates (CANWARD, 2007-18).在产超广谱β-内酰胺酶（ESBL）的临床分离株中，窄谱OXA-1β-内酰胺酶的存在与哌拉西林/他唑巴坦最低抑菌浓度（MIC）值升高有关（CANWARD，2007 - 2018年）。
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PLoS One. 2023 Nov 16;18(11):e0294433. doi: 10.1371/journal.pone.0294433. eCollection 2023.

本文引用的文献

1
Extended-spectrum β-lactamases: an update on their characteristics, epidemiology and detection.超广谱β-内酰胺酶：其特性、流行病学及检测的最新进展
JAC Antimicrob Resist. 2021 Jul 16;3(3):dlab092. doi: 10.1093/jacamr/dlab092. eCollection 2021 Sep.
2
Association Between Minimum Inhibitory Concentration, Beta-lactamase Genes and Mortality for Patients Treated With Piperacillin/Tazobactam or Meropenem From the MERINO Study.美罗培南或哌拉西林/他唑巴坦治疗患者的最低抑菌浓度、β-内酰胺酶基因与死亡率的关系：MERINO 研究。
Clin Infect Dis. 2021 Dec 6;73(11):e3842-e3850. doi: 10.1093/cid/ciaa1479.
3
ResFinder 4.0 for predictions of phenotypes from genotypes.ResFinder 4.0 用于基因型到表型的预测。
J Antimicrob Chemother. 2020 Dec 1;75(12):3491-3500. doi: 10.1093/jac/dkaa345.
4
42936 pathogens from Canadian hospitals: 10 years of results (2007-16) from the CANWARD surveillance study.从加拿大医院采集的 42936 种病原体：CANWARD 监测研究十年（2007-2016 年）的结果。
J Antimicrob Chemother. 2019 Aug 1;74(Suppl 4):iv5-iv21. doi: 10.1093/jac/dkz283.
5
OXA-1 β-lactamase and non-susceptibility to penicillin/β-lactamase inhibitor combinations among ESBL-producing Escherichia coli.产超广谱β-内酰胺酶大肠埃希菌的 OXA-1β-内酰胺酶与对青霉素/β-内酰胺酶抑制剂合剂的不敏感性。
J Antimicrob Chemother. 2019 Feb 1;74(2):326-333. doi: 10.1093/jac/dky453.
6
Effect of Piperacillin-Tazobactam vs Meropenem on 30-Day Mortality for Patients With E coli or Klebsiella pneumoniae Bloodstream Infection and Ceftriaxone Resistance: A Randomized Clinical Trial.哌拉西林-他唑巴坦与美罗培南对产 ESBLs 的大肠埃希菌或肺炎克雷伯菌血流感染且对头孢曲松耐药患者 30 天死亡率的影响：一项随机临床试验。
JAMA. 2018 Sep 11;320(10):984-994. doi: 10.1001/jama.2018.12163.
7
SPAdes: a new genome assembly algorithm and its applications to single-cell sequencing.SPAdes：一种新的基因组组装算法及其在单细胞测序中的应用
J Comput Biol. 2012 May;19(5):455-77. doi: 10.1089/cmb.2012.0021. Epub 2012 Apr 16.