Health Sciences North Research Institute (HSNRI), Sudbury, ON P3E 5J1, Canada.
School of Rural and Northern Health, Laurentian University, Sudbury, ON P3E 2C6, Canada.
Curr Oncol. 2022 Mar 2;29(3):1544-1558. doi: 10.3390/curroncol29030130.
Smoking during cancer treatment is associated with reduced treatment response and cancer recurrence in patients with tobacco-related cancers. The purpose of this study was to examine smoking characteristics in head and neck cancer patients ( = 503) with a history of smoking and examine the impact of an intensive clinical tobacco intervention to patients who were currently smoking. All participants completed an interviewer-administered questionnaire at study enrollment which examined smoking behaviours, motivations to quit, and strategies used to cessate smoking. Follow-up assessments were completed at 6- and 12-months which monitored whether patients had quit smoking, remained cessated, or continued to smoke since study recruitment. For those who were currently smoking ( = 186, 37.0%), an intensive clinical tobacco intervention that utilized the 3A's-Ask, Advise, Arrange-and the Opt-Out approach was offered to assist with smoking cessation at their new patient visit and followed-up weekly during their head and neck radiation therapy for 7 weeks. At 6 months, 23.7% ( = 41) of those who were smoking successfully quit; 51.2% quit 'cold turkey' (defined as using no smoking cessation assistance, aids or pharmacotherapy to quit), while 34.9% used pharmacotherapy (varenicline (Champix)) to quit. On average, it took those who were smoking 1-5 attempts to quit, but once they quit they remained cessated for the duration of the study. Although the head and neck cancer patients in this study reported high levels of nicotine dependence, many were able to successfully cessate.
在癌症治疗期间吸烟与接受与烟草相关癌症治疗的患者的治疗反应降低和癌症复发有关。本研究的目的是检查有吸烟史的头颈部癌症患者(n=503)的吸烟特征,并检查对当前吸烟患者进行强化临床烟草干预的效果。所有参与者在研究入组时都完成了一份由访谈者管理的问卷,该问卷检查了吸烟行为、戒烟动机和戒烟策略。在 6 个月和 12 个月时进行了随访评估,以监测患者是否已戒烟、持续戒烟或自研究招募以来继续吸烟。对于那些目前正在吸烟的患者(n=186,37.0%),在他们的新患者就诊时,提供了强化临床烟草干预,利用 3A 策略-询问、建议、安排-以及选择退出方法,以帮助他们在头颈部放射治疗期间的 7 周内每周戒烟一次。在 6 个月时,23.7%(n=41)正在吸烟的患者成功戒烟;51.2%的人“突然戒烟”(定义为不使用任何戒烟辅助、帮助或药物治疗来戒烟),而 34.9%的人使用药物治疗(伐尼克兰(Champix))来戒烟。平均而言,正在吸烟的患者需要尝试 1-5 次才能戒烟,但一旦戒烟,他们在研究期间就会持续戒烟。尽管本研究中的头颈部癌症患者报告了较高水平的尼古丁依赖,但许多人能够成功戒烟。