[风湿热患者的链球菌感染指标与HLA抗原]
[Indicators of streptococcal infection and HLA antigens in patients with rheumatism].
作者信息
Goriaeva N Iu
出版信息
Ter Arkh. 1986;58(7):60-2.
PMID:3532403
Abstract
A study of histocompatibility antigens in 165 patients with rheumatic fever showed that the most commonly high titers of ASL-O, ASH, ADNAse B were found in the carriers of HLA, A11, B27, CW1, CW2, CW3, DR5 and DR7 antigens which, according to our data, were associated with rheumatic fever. High titers of streptococcal antibodies were found in persons with HLA-A1 and B27.
摘要
一项针对165例风湿热患者的组织相容性抗原研究表明，抗链球菌溶血素O（ASL-O）、抗链球菌透明质酸酶（ASH）、抗脱氧核糖核酸酶B（ADNAse B）的高滴度水平最常见于人类白细胞抗原（HLA）A11、B27、CW1、CW2、CW3、DR5和DR7抗原携带者中，根据我们的数据，这些抗原与风湿热相关。在HLA-A1和B27携带者中发现了高滴度的链球菌抗体。
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