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使用非固定胶原膜和颗粒状骨替代物进行垂直嵴增高的可行性:一项 1 至 7 年回顾性单队列观察研究。

Vertical ridge augmentation feasibility using unfixed collagen membranes and particulate bone substitutes: A 1- to 7-year retrospective single-cohort observational study.

机构信息

Department of Periodontology, Research Institute for Periodontal Regeneration, College of Dentistry, Yonsei University, Seoul, Republic of Korea.

Innovation Research and Support Center for Dental Science, Yonsei University Dental Hospital, Seoul, Republic of Korea.

出版信息

Clin Implant Dent Relat Res. 2022 Jun;24(3):372-381. doi: 10.1111/cid.13084. Epub 2022 Mar 24.

Abstract

AIM

To determine whether vertical ridge augmentation (VRA) can be obtained through guided bone regeneration (GBR) using exclusively resorbable collagen membranes and particulate bone substitutes without additional stabilization.

MATERIALS AND METHODS

This study retrospectively examined 22 participants who underwent VRA with staged or simultaneous implant placement. The vertical defects of all participants were filled with particulate bone substitutes and covered with resorbable collagen membranes. The augmented sites were stabilized with unfixed collagen membranes and the flap without any additional fixation. The augmented tissue height was assessed using cone-beam computed tomography at baseline, immediately after surgery, and at annual follow-ups.

RESULTS

The vertical bone gain of the 22 augmented sites amounted to 6.48 ± 2.19 mm (mean ± SD) immediately after surgery and 5.78 ± 1.72 mm at 1- to 7-year follow-up. Of the 22 augmented sites, 18 exhibited changes of less than 1 mm, while the other 4 showed changes of greater than 1 mm. Histological observation of three representative cases revealed new bone apposition on the remaining material.

CONCLUSION

The present findings indicate that GBR procedures using exclusively collagen membranes and particulate biomaterials without any additional fixation are feasible options for VRA.

摘要

目的

确定在不进行额外固定的情况下,是否可以通过引导骨再生(GBR)技术,仅使用可吸收胶原膜和颗粒状骨替代物来获得垂直骨增量。

材料与方法

本研究回顾性分析了 22 名接受分阶段或同期种植体植入的垂直骨增量患者。所有患者的垂直缺损均用颗粒状骨替代物填充,并覆盖可吸收胶原膜。使用未固定的胶原膜和无任何额外固定的皮瓣来稳定增强部位。使用锥形束计算机断层扫描(CBCT)在基线、术后即刻和每年随访时评估增强组织的高度。

结果

22 个增强部位的垂直骨增量在术后即刻达到 6.48±2.19mm(平均值±标准差),在 1 至 7 年随访时达到 5.78±1.72mm。22 个增强部位中,18 个部位的变化小于 1mm,而另外 4 个部位的变化大于 1mm。对 3 个有代表性的病例进行组织学观察发现,剩余材料上有新骨形成。

结论

本研究结果表明,仅使用胶原膜和颗粒状生物材料,不进行任何额外固定的 GBR 程序是垂直骨增量的可行选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d9d/9314959/100349c87e41/CID-24-372-g004.jpg

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