Verreet P R, Muller C, van Betsbrugge M, Kniemeyer H
Acta Chir Belg. 1986 Jul-Aug;86(4):201-7.
In a prospective multicenter trial the clinical results and recurrences after proximal gastric vagotomy (PGV) in different gastroduodenal ulcer types have been investigated. Pyloric and prepyloric ulcers showed a significantly higher recurrence rate after PGV without drainage than duodenal and gastric ulcers. The secretory pattern could not explain the failure of PGV in these two ulcer types, which exhibit an alteration of the muscular layer at the pylorus and the distal antrum, a so called antropyloric dystrophy. About 60% of the recurrent ulcers after PGV stay asymptomatically. A refined concept for surgical treatment of peptic ulcer is proposed.
在一项前瞻性多中心试验中,研究了不同类型胃十二指肠溃疡行近端胃迷走神经切断术(PGV)后的临床结果和复发情况。幽门溃疡和幽门前溃疡在未行引流的PGV术后复发率明显高于十二指肠溃疡和胃溃疡。分泌模式无法解释这两种溃疡类型PGV手术失败的原因,这两种溃疡类型在幽门和胃窦远端存在肌层改变,即所谓的胃窦幽门营养不良。PGV术后约60%的复发性溃疡无症状。提出了一种更完善的消化性溃疡手术治疗理念。