Bompiani G D, Botta R M
Acta Endocrinol Suppl (Copenh). 1986;277:56-9. doi: 10.1530/acta.0.111s00056.
From 1981 to 1984 90 cases of diabetic pregnancy were seen at the Palermo Center. Twenty-nine patients (32%) had prepregnancy type 2 diabetes, 20 (69%) of these were obese and were studied further. The patients were divided into 2 groups of 13 and 7 patients. The first group was given a diet of 30 kcal/kg ideal prepregnancy weight. The second group was prescribed a low energy diet of on average 1200 kcal/day. In the diet-restricted group, weight gain was less pronounced (7.9 +/- 1.2 SD vs. 12.7 +/- 8.6 kg), insulin requirement was lower (0.56 +/- 0.22 vs. 1.00 +/- 0.34 U/kg body weight) and the metabolic control was better than observed in the group given 30 kcal/kg body weight. The weight gain during pregnancy was proportional to the fetal weight index at birth (r = 0.72, P less than 0.0005). It is concluded that obese type 2 diabetic women are best treated by a low caloric diet and, when necessary, small doses of insulin. To establish the optimal caloric intake for obese pregnant type 2 diabetic women, the following formula is proposed: (30 kcal/kg prepregnancy ideal body weight/24 h) - X, where X is the % of prepregnancy obesity exceeding 120.
1981年至1984年期间，巴勒莫中心共收治90例糖尿病合并妊娠患者。29例（32%）患者孕前即患有2型糖尿病，其中20例（69%）为肥胖患者，并对其进行了进一步研究。将这些患者分为两组，一组13例，另一组7例。第一组给予的饮食量为每千克孕前理想体重30千卡。第二组规定的低能量饮食平均每天1200千卡。在饮食限制组中，体重增加不太明显（7.9±1.2标准差 vs. 12.7±8.6千克），胰岛素需求量较低（0.56±0.22 vs. 1.00±0.34单位/千克体重），代谢控制情况优于给予每千克体重30千卡饮食的组。孕期体重增加与出生时的胎儿体重指数成正比（r = 0.72，P＜0.0005）。得出的结论是，肥胖的2型糖尿病女性最好采用低热量饮食治疗，必要时辅以小剂量胰岛素。为确定肥胖的2型糖尿病孕妇的最佳热量摄入量，提出以下公式：（每千克孕前理想体重30千卡/24小时）-X，其中X是孕前肥胖超过120的百分比。
