Department of Otorhinolaryngology Head and Neck Surgery, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico S.Orsola-Malpighi, 40138 Bologna, Italy.
Department of Specialist, Diagnostic and Experimental Medicine (DIMES), Alma Mater Studiorum, Università di Bologna, 40138 Bologna, Italy.
Int J Environ Res Public Health. 2022 Mar 19;19(6):3657. doi: 10.3390/ijerph19063657.
Nowadays, head and neck surgical approaches need an increased level of anatomical knowledge and practical skills; therefore, the related learning curve is both flat and long. On such procedures, surgeons must decrease operating time as much as possible to reduce the time of general anesthesia and related stress factors for patients. Consequently, little time can be dedicated for training skills of students and young residents in the operating theater. Fresh human cadavers offer the most obvious surrogate for living patients, but they have several limitations, such as cost, availability, and local regulations. Recently, the feasibility of using ex vivo animal models, in particular ovine ones, have been considered as high-fidelity alternatives to cadaveric specimens. : This comprehensive review explores all of head and neck otolaryngology applications with this sample. We analyzed studies about ear surgery, orbital procedures, parotid gland and facial nerve reanimation, open laryngeal and tracheal surgery, microlaryngoscopy procedures, laryngotracheal stenosis treatment, and diagnostic/operative pediatric endoscopy. For each different procedure, we underline the main applications, similarities, and limitations to human procedures so as to improve the knowledge of this model as a useful tool for surgical training. : An ovine model is easily available and relatively inexpensive, it has no limitations associated with religious or animal ethical issues, and it is reliable for head and neck surgery due to similar consistencies tissues and neurovascular structures with respect to humans. However, some other issues should be considered, such as differences about some anatomical features, the risk of zoonotic diseases, and the absence of bleeding during training. : This comprehensive review highlights the potentials of an ex vivo ovine model and aims to stimulate the scientific and academic community to further develop it for other applications in surgical education.
如今,头颈部外科手术需要更高水平的解剖学知识和实践技能;因此,相关的学习曲线既平坦又漫长。在这些手术中,外科医生必须尽可能缩短手术时间,以减少患者全身麻醉和相关应激因素的时间。因此,在手术室里,留给学生和年轻住院医师训练技能的时间很少。新鲜的人体尸体为活体患者提供了最明显的替代品,但它们存在一些局限性,如成本、可用性和当地法规。最近,使用离体动物模型,特别是绵羊模型,作为尸体标本的高保真替代品的可行性已经得到了考虑。
这篇全面的综述探讨了使用这种样本的所有头颈部耳鼻喉科应用。我们分析了关于耳部手术、眼眶手术、腮腺和面神经再支配、开放式喉和气管手术、显微喉镜手术、喉气管狭窄治疗以及诊断/手术儿科内窥镜的研究。对于每种不同的手术,我们强调了与人类手术的主要应用、相似性和局限性,以提高对这种模型作为手术培训有用工具的认识。
绵羊模型易于获得且相对便宜,它没有与宗教或动物伦理问题相关的限制,并且由于与人类相似的组织和神经血管结构,对头颈手术非常可靠。然而,还应该考虑其他一些问题,例如一些解剖特征的差异、人畜共患疾病的风险以及在训练过程中没有出血的情况。
这篇全面的综述强调了离体绵羊模型的潜力,并旨在激发科学界和学术界进一步将其开发用于手术教育中的其他应用。