Abed Faisal Mohammed, Kotha Sunil Babu, AlShukairi Haneen, Almotawah Fatmah Nasser, Alabdulaly Rwan Abdulali, Mallineni Sreekanth Kumar
Ministry of Health Specialized Dental Center, King Fahd General Hospital, Madinah, Saudi Arabia.
Department of Preventive Dentistry, College of Dentistry, Riyadh Elm University (REU), Riyadh, Saudi Arabia.
Front Bioeng Biotechnol. 2022 Mar 7;10:816652. doi: 10.3389/fbioe.2022.816652. eCollection 2022.
The nanotechnologies have been applied for dental restorative materials manufacturing such as glass ionomer cement, composites, tooth regeneration, and endodontic sealers. The study aimed to investigate the chemical bond of conventional glass ionomer cement and to evaluate the addition of different concentrations of silver nanoparticles (AgNPs) on the quality of the chemical bond of glass ionomer cement to primary dentin. Silver nanoparticle (AgNP) powder was added in concentrations of 0.2, 0.4, and 0.6% to the conventional powder of GIC Fuji II. Then, the powder was added to the liquid and mixed with the recommended powder/liquid ratio of 3.6:1 g. The Fourier-transform infrared spectra (FTIR) of teeth with 0.2%, 0.4%, and 0.6% w/w of silver nanoparticles in GIC fills and the control tooth were obtained. The conventional glass ionomer was used as a control group. The control and the plain silver tooth were subjected to FTIR analysis using an ATR-FTIR spectrophotometer (ThermoFisher Scientific, Waltham, MA, United States) with zinc selenide (ZnSe) ATR crystal (attenuated total reflection) and OPUS v7.5 software. All spectra were recorded in the range of 500-3,500 cm in the transmission mode with an ATR module. The AgNPs added at 0.2, 0.4, and 0.6% concentration to GIC provided some information in the context of bond interaction with the dentin. Various bond peaks were seen for calcium, carbonate, phosphate, and amide. In our study, only the amide and phosphate were generated. The amide peaks were almost similar to the control, 0.2%, 0.4%, and 0.6%, with the peaks in the range of 1250-1650 cm. There was a clear shift in the phosphate peak from the control, 0.2, and 0.4%, which was about 1050 cm, whereas for 0.6%, there was a clear shift from 1050 cm to 880 cm. GIC supplemented with AgNPs showed that a concentration above 0.4% of AgNPs altered the bond quality in dentin interaction. In conclusion, adding AgNPs at a minimal level improves the mechanical properties and maintains the same bond quality as GIC.
纳米技术已应用于牙科修复材料的制造，如玻璃离子水门汀、复合材料、牙齿再生和根管封闭剂。该研究旨在探究传统玻璃离子水门汀的化学键，并评估添加不同浓度的银纳米颗粒（AgNPs）对玻璃离子水门汀与乳牙本质化学键质量的影响。将浓度为0.2%、0.4%和0.6%的银纳米颗粒（AgNP）粉末添加到传统的富士II型玻璃离子水门汀粉末中。然后，将该粉末加入液体中，并按照推荐的3.6:1 g的粉液比进行混合。获取了玻璃离子水门汀填充物中银纳米颗粒含量为0.2%、0.4%和0.6%（重量/重量）的牙齿以及对照牙齿的傅里叶变换红外光谱（FTIR）。将传统玻璃离子水门汀用作对照组。使用配备硒化锌（ZnSe）衰减全反射（ATR）晶体和OPUS v7.5软件的ATR - FTIR分光光度计（美国赛默飞世尔科技公司，马萨诸塞州沃尔瑟姆）对对照组和纯银牙齿进行FTIR分析。所有光谱均在500 - 3500 cm范围内以透射模式通过ATR模块进行记录。添加到玻璃离子水门汀中的浓度为0.2%、0.4%和0.6%的银纳米颗粒在与牙本质的键相互作用方面提供了一些信息。观察到钙、碳酸盐、磷酸盐和酰胺的各种键峰。在我们的研究中，仅产生了酰胺和磷酸盐。酰胺峰在1250 - 1650 cm范围内，在对照组、0.2%、0.4%和0.6%组中几乎相似。磷酸盐峰相对于对照组、0.2%和0.4%组有明显位移，约为1050 cm，而对于0.6%组，从1050 cm明显位移至880 cm。添加银纳米颗粒的玻璃离子水门汀表明，银纳米颗粒浓度高于0.4%会改变与牙本质相互作用中的键质量。总之，最低限度添加银纳米颗粒可改善机械性能并保持与玻璃离子水门汀相同的键质量。
