Department of Psychology, University of Jyväskylä, Jyväskylä, Finland.
Faculty of Health and Sport, University of Agder, Kristiansand, Norway.
Early Interv Psychiatry. 2022 Dec;16(12):1368-1375. doi: 10.1111/eip.13286. Epub 2022 Mar 25.
To evaluate the 10-year treatment outcomes and cost-effectiveness of adolescents' mental health treatment initiated under the social network-oriented open dialogue (OD) approach.
This longitudinal register-based study included all persons who, for the first time, received psychiatric treatment in Finland during the period 1 January 2003-31 December 2008, and who were aged 13-20 at onset (n = 44 868). The OD group included all persons whose treatment commenced in the Western Lapland catchment area (n = 780), this being the only region in Finland where OD covered the entire mental healthcare service at the time of inclusion. The comparison group (CG) included the rest of Finland (n = 44 088). The primary outcome variables were psychiatric treatment and/or disability allowances at the end of the 10-year follow-up, or death. The secondary outcome variables were treatment and disability expenses. Generalized linear models weighted by inverse probability of treatment were used to study the association between OD and the primary outcomes. Population proportions were used to evaluate the cost-effectiveness of the approaches.
Treatment that commenced outside OD was associated with higher odds of continuing to receive treatment (adjusted odds ratio [aOR] 1.4; 95%CI 1.2-1.6) and disability allowances (aOR 1.6; 95%CI 1.2-2.1) at the end of the 10-year follow-up. No significant difference in the mortality ratio emerged. The cumulative 10-year expenses per capita were lower under OD.
OD associated with favourable long-term outcomes, but due the observational design and possible residual confounding, further studies with a more robust research design are required.
评估以社交网络为导向的开放式对话(OD)方法启动的青少年心理健康治疗的 10 年治疗结果和成本效益。
本纵向基于登记的研究纳入了所有于 2003 年 1 月 1 日至 2008 年 12 月 31 日期间首次在芬兰接受精神科治疗且发病时年龄在 13-20 岁的患者(n=44868)。OD 组包括所有在西拉普兰地区(n=780)开始治疗的患者,这是芬兰唯一在纳入时将 OD 覆盖整个精神卫生保健服务的地区。对照组(CG)包括芬兰其他地区(n=44088)。主要结局变量是在 10 年随访结束时的精神科治疗和/或残疾津贴,或死亡。次要结局变量是治疗和残疾费用。使用加权逆概率治疗的广义线性模型来研究 OD 与主要结局之间的关联。使用人口比例来评估方法的成本效益。
OD 以外的治疗与在 10 年随访结束时继续接受治疗(调整优势比[aOR]1.4;95%CI 1.2-1.6)和残疾津贴(aOR 1.6;95%CI 1.2-2.1)的几率更高相关。死亡率比没有出现显著差异。OD 下的人均累计 10 年费用较低。
OD 与有利的长期结果相关,但由于观察性设计和可能存在的残余混杂因素,需要进一步采用更稳健的研究设计进行研究。