Department of Psychology, University of Jyväskylä, Jyväskylä, Finland.
Department of Psychology, University of Jyväskylä, Jyväskylä, Finland.
Psychiatry Res. 2018 Dec;270:168-175. doi: 10.1016/j.psychres.2018.09.039. Epub 2018 Sep 18.
Open Dialogue (OD) is a family-oriented early intervention approach which has demonstrated good outcomes in the treatment of first-episode psychosis (FEP). Nevertheless, more evidence is needed. In this register-based cohort study the long-term outcomes of OD were evaluated through a comparison with a control group over a period of approximately 19 years. We examined the mortality, the need for psychiatric treatment, and the granting of disability allowances. Data were obtained from Finnish national registers regarding all OD patients whose treatment for FEP commenced within the time of the original interventions (total N = 108). The control group consisted of all Finnish FEP patients who had a follow-up of 19-20 years and who were guided to other Finnish specialized mental healthcare facilities (N = 1763). No difference between the samples was found regarding the annual incidence of FEP, the diagnosis, and suicide rates. Over the entire follow-up, the figures for durations of hospital treatment, disability allowances, and the need for neuroleptics remained significantly lower with OD group. Findings indicated that many positive outcomes of OD are sustained over a long time period. Due to the observational nature of the study, randomized trials are still needed to provide more information on effectiveness of approach.
开放对话(Open Dialogue,OD)是一种以家庭为导向的早期干预方法,在治疗首发精神病(first-episode psychosis,FEP)方面已显示出良好的效果。然而,仍需要更多的证据。在这项基于登记的队列研究中,通过与对照组进行比较,评估了 OD 的长期结果,随访时间约为 19 年。我们研究了死亡率、精神科治疗需求和残疾津贴的发放情况。数据来自芬兰全国登记处,涉及所有在原始干预期间开始接受 FEP 治疗的 OD 患者(共 108 名)。对照组由所有在随访 19-20 年后被引导至其他芬兰专门精神保健机构的芬兰 FEP 患者组成(共 1763 名)。两组在 FEP 的年发病率、诊断和自杀率方面没有差异。在整个随访期间,OD 组的住院治疗时间、残疾津贴和需要使用神经阻滞剂的时间明显较短。研究结果表明,OD 的许多积极结果可以持续很长时间。由于研究的观察性质,仍需要随机试验来提供更多关于该方法有效性的信息。