Department of Surgery, 609772Duke University Medical Center, Durham, NC, USA.
Pratt School of Engineering, 101571Duke University, Durham, NC, USA.
Am Surg. 2022 Aug;88(8):1901-1903. doi: 10.1177/00031348221086783. Epub 2022 Mar 25.
The COVID-19 pandemic has resulted in the exposure of many surgeons and healthcare providers (HCPs) to disease given high patient loads and limited availability of negative pressure rooms. For these reasons we pursued the development of a portable patient isolation system (COVIAGE™ by iSolace, Inc.) that can be used to contain patients with respiratory illness and minimize the exposure of HCPs. COVIAGE™ is comprised of a reusable aluminum frame, a disposable thermoplastic polyurethane tent and a HEPA filtration/ventilation system (HVAC) utilizing two inline filters. The efficacy of filtration was tested by comparing particulate concentration inside and outside of the device by an independent third party. Additionally, physician, nursing, and respiratory tasks were performed initially on simulated patients and then on intubated patients in the ICU. The system attained a verified filtration efficiency greater than 99.999% for an average 0.3-μm size particulates. Simulation testing revealed that most common physician, nursing, and respiratory tasks could be completed in the device, including endotracheal intubation. Emergency removal of the device can be accomplished in 8.8 ± 2.8 seconds. The reusable aluminum frame allows for simple attachment to the bed, and adaptability to different types and sizes of beds/stretchers. An emergency use authorization was granted by the FDA. The device created results in a portable negative pressure isolation system that can be placed over the patient's bed to contain aerosols during high aerosol generating procedures, transportation of patients or for total patient care in environments where negative pressure rooms are not available.
COVID-19 大流行导致许多外科医生和医疗保健提供者（HCP）接触到疾病，因为患者数量高，负压室的可用性有限。出于这些原因，我们开发了一种便携式患者隔离系统（iSolace 公司的 COVIAGE™），可用于容纳患有呼吸道疾病的患者，并最大限度地减少 HCP 的暴露。COVIAGE™ 由可重复使用的铝制框架、一次性热塑性聚氨酯帐篷和一个利用两个在线过滤器的高效空气微粒过滤/通风系统（HVAC）组成。第三方独立测试了过滤效果，比较了设备内外的颗粒浓度。此外，最初在模拟患者身上进行了医生、护理和呼吸任务，然后在 ICU 中对插管患者进行了这些任务。该系统的平均 0.3-μm 尺寸颗粒过滤效率达到 99.999%以上。模拟测试表明，大多数常见的医生、护理和呼吸任务都可以在设备中完成，包括气管插管。紧急情况下可以在 8.8 ± 2.8 秒内移除设备。可重复使用的铝制框架允许简单地连接到床上，并适应不同类型和大小的床/担架。FDA 已授予紧急使用授权。该设备产生的结果是一种便携式负压隔离系统，可以放置在患者的床上，以在高气溶胶产生程序、患者转运或在没有负压室的环境中进行全面患者护理期间容纳气溶胶。
