Department of Gastroenterology, Tokyo Bay Urayasu Ichikawa Medical Center, 3-4-32, Todaijima, Urayasu, Chiba, 279-0001, Japan.
Department of General Internal Medicine, Tokyo Bay Urayasu Ichikawa Medical Center, 3-4-32, Todaijima, Urayasu, Chiba, 279-0001, Japan.
Clin J Gastroenterol. 2022 Jun;15(3):673-679. doi: 10.1007/s12328-022-01624-6. Epub 2022 Mar 25.
Peripancreatic tuberculous lymphadenopathy can mimic pancreatic cancer on imaging. There have only a few reports on varices from portal vein obstruction due to abdominal tuberculous lymphadenopathy. Iatrogenic disseminated tuberculosis is also rare. Herein, we present a rare case of peripancreatic tuberculous lymphadenopathy with ruptured duodenal varices due to portal vein obstruction. The patient presented to our hospital with hematemesis. Computed tomography revealed a peripancreatic mass. Duodenal varices rupture from portal vein obstruction due to pancreatic cancer were initially suspected. The patient underwent portal vein stenting for portal vein obstruction and endoscopic ultrasound-guided fine-needle aspiration for diagnosis, which revealed granulomas indicative of tuberculosis. The patient was discharged once because fine-needle aspiration did not lead to a definitive diagnosis of tuberculosis. Subsequently, he developed disseminated tuberculosis. Peripancreatic tuberculous lymphadenopathy can cause ectopic varices with portal vein obstruction. Tuberculosis should also be included in the differential diagnosis in the case of portal vein obstruction, to facilitate early treatment and avoid unnecessary surgery. Furthermore, fine-needle aspiration or portal vein stenting for tuberculous lesions can cause disseminated tuberculosis. Since a diagnosis might not be made until after several fine-needle aspirations have been conducted, careful follow-up is necessary after the procedure for such lesions.
胰周结核性淋巴结病在影像学上可类似于胰腺癌。由于腹部结核性淋巴结病导致门静脉阻塞而引起食管胃底静脉曲张的报道仅有少数几例。医源性播散性结核也很少见。本文报告了一例罕见的胰周结核性淋巴结病伴因门静脉阻塞所致十二指肠静脉曲张破裂的病例。该患者因呕血就诊于我院。计算机断层扫描显示胰周肿块。最初怀疑是由于胰腺癌导致的门静脉阻塞引起的十二指肠静脉曲张破裂。该患者因门静脉阻塞而行门静脉支架置入术,为明确诊断而行内镜超声引导下细针抽吸术,结果显示提示结核的肉芽肿。由于细针抽吸术未明确诊断为结核病,该患者曾出院一次。随后,他发生了播散性结核。胰周结核性淋巴结病可引起门静脉阻塞性异位静脉曲张。在门静脉阻塞的情况下,也应将结核病纳入鉴别诊断,以方便早期治疗并避免不必要的手术。此外,对结核病变进行细针抽吸或门静脉支架置入术可能会导致播散性结核。由于在进行多次细针抽吸后才可能确诊,因此对于此类病变,在操作后需要仔细随访。