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花粉过敏:为中低收入国家制定预防和控制花粉过敏的多部门策略。

Pollen allergy: Developing multi-sectorial strategies for its prevention and control in lower and middle-income countries.

机构信息

Department of Community Medicine and School of Public Health, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India.

Department of Environment Studies, Panjab University, Chandigarh, 160014, India.

出版信息

Int J Hyg Environ Health. 2022 May;242:113951. doi: 10.1016/j.ijheh.2022.113951. Epub 2022 Mar 22.

Abstract

Pollen allergy is considered a major public health problem that causes morbidity and subsequently affects a patient's quality of life. Pollen due to their large size cannot enter the thoracic regions of the respiratory tract but can affect the nasopharyngeal mucous membrane. At the same time, the submicronic-pollen particles can act as respirable particles reaching deeper into the upper airways leading to exacerbation of asthma, chronic obstructive pulmonary disease (COPD) and other allergic reactions. Based on the existing literature, expanding evidence shows that climate change and air pollutants could affect the pollen number, morphology, season, allergen content, and distribution pattern. Hence, this will influence the prevalence and occurrence of allergies linked to pollen exposure. Being a part of biogenic pollutants, pollen allergens are not expected to diminish in the foreseeable future. Therefore, it is imperative that steps need to be strengthened to improve and optimize preventive/adaptive strategies. This paper aims to review the major causes of widespread allergy, identify the major gaps, and suggest key preventive/adaptive measures to address the onset and exacerbation of pollen-related allergic diseases with a major focus on lower and middle-income countries. The study also discusses how-to implement the prevention and control measures at the individual, health care communities and organizations, Local Governments, National/International Governments levels to decrease the risk of illnesses associated with pollen allergy.

摘要

花粉过敏被认为是一个主要的公共卫生问题,它会导致发病率上升,进而影响患者的生活质量。花粉由于体积较大,无法进入呼吸道的胸腔区域,但会影响鼻咽黏膜。同时,亚微米花粉颗粒可以作为可吸入颗粒进入上呼吸道的更深部位,导致哮喘、慢性阻塞性肺疾病(COPD)和其他过敏反应恶化。基于现有文献,越来越多的证据表明,气候变化和空气污染物会影响花粉数量、形态、季节、过敏原含量和分布模式。因此,这将影响与花粉暴露有关的过敏症的流行和发生。作为生物源污染物的一部分,花粉过敏原在可预见的未来预计不会减少。因此,必须加强措施,以改善和优化预防/适应策略。本文旨在综述广泛过敏的主要原因,确定主要差距,并提出关键的预防/适应措施,以解决与花粉相关的过敏性疾病的发病和恶化问题,重点关注中低收入国家。该研究还讨论了如何在个人、医疗保健社区和组织、地方政府、国家/国际政府各级实施预防和控制措施,以降低与花粉过敏相关的疾病风险。

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