Vogelberg K H, Rathmann W
Dtsch Med Wochenschr. 1986 Oct 31;111(44):1687-91. doi: 10.1055/s-2008-1068693.
Antral contraction after a test meal was measured by ultrasonography in 32 insulin-dependent diabetics with and without autonomic neuropathy and in 12 control subjects. In sequence of the three groups studied the results were: frequency of contractions 3.6 +/- 2.0, 4.8 +/- 1.6, and 4.8 +/- 1.6, respectively, per two minutes; intensity of contraction 30.9 +/- 8.2, 41.4 +/- 5.2 and 57.5 +/- 8.8% of maximal antral surface decrease; and contraction velocity per sec 4.8 +/- 1.5, 8.2 +/- 1.2 and 9.95 +/- 2.8% of maximal antral surface decrease. Different from the frequency, intensity and velocity of antral contraction were reduced in diabetics (compared with normal controls) even without an autonomic neuropathy. In all diabetics, contraction velocity was positively correlated to variations in heart rate and to the postprandial blood-glucose rise. The results indicate that disorders of motility in diabetics with autonomic neuropathy can be visualized by ultrasonography and can be diagnosed early from a reduction in contraction velocity.
通过超声检查测量了32例有或无自主神经病变的胰岛素依赖型糖尿病患者以及12名对照者在试餐后的胃窦收缩情况。在所研究的三组中,结果依次如下:每两分钟的收缩频率分别为3.6±2.0、4.8±1.6和4.8±1.6;收缩强度分别为最大胃窦表面积减少的30.9±8.2%、41.4±5.2%和57.5±8.8%;每秒的收缩速度分别为最大胃窦表面积减少的4.8±1.5%、8.2±1.2%和9.95±2.8%。与频率不同,即使没有自主神经病变,糖尿病患者(与正常对照相比)的胃窦收缩强度和速度也降低。在所有糖尿病患者中,收缩速度与心率变化以及餐后血糖升高呈正相关。结果表明,自主神经病变的糖尿病患者的运动障碍可以通过超声检查显示出来,并且可以通过收缩速度的降低早期诊断。