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Effects of magnesium and sodium ions on the outer membrane permeability of cephalosporins in Escherichia coli.

作者信息

Yamaguchi A, Yanai M, Tomiyama N, Sawai T

出版信息

FEBS Lett. 1986 Nov 10;208(1):43-7. doi: 10.1016/0014-5793(86)81528-9.

DOI:10.1016/0014-5793(86)81528-9
PMID:3533634
Abstract

Both Mg2+ and Na+ stimulated the outer membrane permeation of negatively charged cephalosporins in Escherichia coli without any significant alteration of the permeation of a zwitterionic cephalosporin. Such stimulation was not observed in an E. coli mutant lacking porins. The stimulation was caused by the direct interaction between the cations and the porin pores, which resulted in a decrease in cation selectivity of both the Omp F and Omp C porin pores.

摘要

相似文献

1
Effects of magnesium and sodium ions on the outer membrane permeability of cephalosporins in Escherichia coli.
FEBS Lett. 1986 Nov 10;208(1):43-7. doi: 10.1016/0014-5793(86)81528-9.
2
Difference in pathway of Escherichia coli outer membrane permeation between penicillins and cephalosporins.
FEBS Lett. 1985 Feb 11;181(1):143-8. doi: 10.1016/0014-5793(85)81130-3.
3
Identification of porins in outer membrane of Proteus, Morganella, and Providencia spp. and their role in outer membrane permeation of beta-lactams.变形杆菌属、摩根菌属和普罗威登斯菌属外膜中孔蛋白的鉴定及其在β-内酰胺类药物外膜渗透中的作用。
Antimicrob Agents Chemother. 1987 Mar;31(3):379-84. doi: 10.1128/AAC.31.3.379.
4
Porin channels in intact cells of Escherichia coli are not affected by Donnan potentials across the outer membrane.
J Biol Chem. 1988 Jan 25;263(3):1182-7.
5
Decreased permeation of cephalosporins through the outer membrane of Escherichia coli grown in salicylates.头孢菌素透过在水杨酸盐中生长的大肠杆菌外膜的渗透率降低。
Antimicrob Agents Chemother. 1989 Apr;33(4):412-7. doi: 10.1128/AAC.33.4.412.
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Porin channels in Escherichia coli: studies with beta-lactams in intact cells.大肠杆菌中的孔蛋白通道:在完整细胞中使用β-内酰胺类药物的研究
J Bacteriol. 1983 Jan;153(1):232-40. doi: 10.1128/jb.153.1.232-240.1983.
7
Recognition site for phosphorus-containing compounds and other negatively charged solutes on the PhoE protein pore of the outer membrane of Escherichia coli K12.大肠杆菌K12外膜PhoE蛋白孔上含磷化合物及其他带负电荷溶质的识别位点。
Eur J Biochem. 1982 Aug;126(1):113-8. doi: 10.1111/j.1432-1033.1982.tb06754.x.
8
The mechanism of ion selectivity of OmpF-porin pores of Escherichia coli.大肠杆菌OmpF孔蛋白通道的离子选择性机制。
Eur J Biochem. 1985 Sep 2;151(2):231-6. doi: 10.1111/j.1432-1033.1985.tb09093.x.
9
Outer membrane permeability of Acinetobacter calcoaceticus and its implication in antibiotic resistance.
J Antimicrob Chemother. 1991 Jul;28(1):35-45. doi: 10.1093/jac/28.1.35.
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Role of porins in intrinsic antibiotic resistance of Pseudomonas cepacia.
Antimicrob Agents Chemother. 1987 Jan;31(1):121-3. doi: 10.1128/AAC.31.1.121.

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