Hatton Randy C, Hendeles Leslie
Department of Pharmaceutical Outcomes and Policy, College of Pharmacy, University of Florida, Fernandina Beach, FL, USA.
Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA.
Ann Pharmacother. 2022 Mar 25:10600280221081526. doi: 10.1177/10600280221081526.
Ineffective over-the-counter (OTC) drugs should be removed from the US market. Despite solid research showing that oral phenylephrine is ineffective as a decongestant, the US Food and Drug Administration has failed to respond to a 2015 citizen's petition to remove it from the OTC nasal decongestant monograph. Other examples of scientifically proven ineffective OTC medications include guaifenesin as an expectorant, dextromethorphan as a cough suppressant, and chlorpheniramine for cold symptoms.
无效的非处方药应从美国市场下架。尽管有确凿研究表明口服去氧肾上腺素作为减充血剂无效，但美国食品药品监督管理局并未对2015年要求将其从非处方鼻腔减充血剂专著中移除的公民请愿作出回应。其他经科学证实无效的非处方药物包括作为祛痰剂的愈创甘油醚、作为止咳剂的右美沙芬以及用于缓解感冒症状的氯苯那敏。
