Beelen D W, Mahmoud H K, Mlynek M L, Schmidt U, Richter H J, Schaefer U W
Immun Infekt. 1986 Sep;14(5):183-7.
An opportunistic infection with Toxoplasma gondii is a rare complication in the immunocompromised host following bone marrow transplantation. In addition to the variability in the clinical picture, difficulty in interpretation of the antibody titers is one of the main obstacles limiting early diagnosis of manifest toxoplasmosis. This report deals with 3 patients out of 86 bone marrow transplant recipients who had manifest toxoplasmosis mainly affecting the central nervous system and cardiac muscle. The clinical picture was that of acute disseminated encephalitis and myocarditis, while the nature of the disease was only disclosed at autopsy.
弓形虫机会性感染是骨髓移植后免疫功能低下宿主中罕见的并发症。除临床表现存在差异外,抗体滴度解释困难是限制显性弓形虫病早期诊断的主要障碍之一。本报告涉及86例骨髓移植受者中的3例,这些患者患有主要影响中枢神经系统和心肌的显性弓形虫病。临床表现为急性播散性脑炎和心肌炎,而该病的性质仅在尸检时才被发现。