Environmental Health Research Centre, Institute for Medical Research, Ministry of Health Malaysia, 40170, Shah Alam, Selangor, Malaysia.
Environmental Health Research Centre, Institute for Medical Research, Ministry of Health Malaysia, 40170, Shah Alam, Selangor, Malaysia.
Food Chem Toxicol. 2022 May;163:112949. doi: 10.1016/j.fct.2022.112949. Epub 2022 Mar 23.
Recently, there has been an increasing ecological and global public health concern associated with environmental contamination by arsenic (As), cadmium (Cd), nickel (Ni) and lead (Pb). This study aims to visualize distribution of these heavy metals concentration in urine of 817 Malaysian adults in Malaysia. This cross-sectional study compiled urine samples from October 2017 to March 2018. Spatial inverse distance weighted (IDW) interpolation method was used to derive a map which illustrate the distribution of these metals from urine samples. Moran's I Index was used to assess the spatial autocorrelation of these metals between the study area. The mean concentration for Ni and Cd was highest in Perak while for As and Pb, they were predominantly in East Coast region (Terengganu and Kelantan). Moran's I index showed significant spatial autocorrelation exist in the study area for all metals except for Pb (p-value<0.05). According to IDW, people in North East and Western regions had the highest concentrations for As and Cd. Individuals in Central region were less exposed than those in North region. These techniques can assist health authorities a better prediction in assessing exposure to heavy metals in population of an area to prioritize their control and preventive measure.
最近,砷(As)、镉(Cd)、镍(Ni)和铅(Pb)等重金属对环境的污染引起了越来越多的生态和全球公共卫生关注。本研究旨在直观呈现 817 名马来西亚成年人尿液中这些重金属浓度的分布情况。本横断面研究于 2017 年 10 月至 2018 年 3 月期间收集了尿液样本。空间反距离权重(IDW)插值方法用于绘制地图,以说明尿液样本中这些金属的分布情况。莫兰指数(Moran's I Index)用于评估研究区域内这些金属之间的空间自相关关系。镍(Ni)和镉(Cd)的平均浓度在霹雳州最高,而砷(As)和铅(Pb)则主要集中在东海岸地区(登嘉楼和吉兰丹)。除铅(Pb)外(p 值<0.05),莫兰指数(Moran's I Index)显示研究区域内所有金属均存在显著的空间自相关。根据 IDW,东北地区和西部地区的人群砷(As)和镉(Cd)的浓度最高。与北部地区相比,中部地区的人群暴露程度较低。这些技术可以帮助卫生当局更好地预测和评估特定地区人群对重金属的暴露情况,以便优先采取控制和预防措施。