The Biosensor National Special Laboratory, College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou 310027, People's Republic of China.
The Biosensor National Special Laboratory, College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou 310027, People's Republic of China.
Photodiagnosis Photodyn Ther. 2022 Jun;38:102826. doi: 10.1016/j.pdpdt.2022.102826. Epub 2022 Mar 23.
Endoscopies are crucial for detecting and diagnosing diseases in gastroenterology, pulmonology, urology, and other fields. To accurately diagnose diseases, sample biopsies are indispensable and are currently considered the gold standard. However, random 4-quadrant biopsies have sampling errors and time delays. To provide intraoperative real-time microscopic images of suspicious lesions, microscopic endoscopy for in vivo optical biopsy has been developed, including endocytoscopy and confocal laser endomicroscopy. This article reviews recent advances in technology and clinical applications, as well as their shortcomings and future directions.
内窥镜检查在消化内科、呼吸内科、泌尿科和其他领域的疾病检测和诊断中至关重要。为了准确诊断疾病，样本活检是不可或缺的，目前被认为是金标准。然而，随机的 4 象限活检存在采样误差和时间延迟。为了提供可疑病变的术中实时微观图像，已经开发了用于体内光学活检的微观内窥镜检查，包括细胞内镜检查和共聚焦激光内窥镜检查。本文综述了该技术的最新进展和临床应用，以及它们的缺点和未来方向。
