Department of Dermatovenereology, Ljubljana University Medical Centre, Ljubljana, Slovenia.
Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Acta Dermatovenerol Alp Pannonica Adriat. 2022 Mar;31(Suppl):S7-S9.
Filariasis is a parasitic disease caused by infection with roundworms of the Filarioidea superfamily. Depending on the species of roundworm, the disease can present itself in one of three forms. It can affect the lymphatic system, the subcutaneous tissue, or serous cavities. We present the case of a male patient from central Europe with a subcutaneous manifestation similar to filariasis. Laboratory findings showed eosinophilia and elevated levels of IgE antibodies, and histological examination of skin biopsy material showed granulation tissue with lymphoid and plasma cell infiltration. When the lesion was examined under a microscope following an excision, live wormlike parasites about 3.5 cm long were detected. Such parasitic infections are usually encountered in tropical regions and sometimes reported in travelers returning from endemic countries. Our patient, however, had never left Europe, which is what makes this case so interesting.
丝虫病是一种由旋毛线虫超科的线虫感染引起的寄生虫病。根据线虫的种类,疾病可以表现为以下三种形式之一。它可以影响淋巴系统、皮下组织或浆膜腔。我们报告了一位来自中欧的男性患者,其皮下表现类似于丝虫病。实验室检查显示嗜酸性粒细胞增多和 IgE 抗体水平升高,皮肤活检材料的组织学检查显示肉芽组织伴淋巴细胞和浆细胞浸润。切除后在显微镜下检查病变时,发现了大约 3.5 厘米长的类似活虫的寄生虫。这种寄生虫感染通常在热带地区遇到,有时也有从流行地区返回的旅行者报告。然而,我们的患者从未离开过欧洲,这使得这个病例非常有趣。