冠状动脉钙化评分作为COVID-19患者不良结局的预后因素：一项综述
Coronary artery calcium score as a prognostic factor of adverse outcomes in patients with COVID-19: a comprehensive review.
作者信息
Yousefimoghaddam Fateme, Goudarzi Ehsan, Ramandi Alireza, Khaheshi Isa
机构信息
Cardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
School of Medicine, Tehran University of Medical Sciences, Tehran, Iran; Students' Scientific Research Center (SSRC), Tehran University of Medical Sciences, Tehran, Iran.
出版信息
Curr Probl Cardiol. 2023 Aug;48(8):101175. doi: 10.1016/j.cpcardiol.2022.101175. Epub 2022 Mar 24.
BACKGROUND AND AIM
The association of known cardiovascular risk factors and poor prognosis of coronavirus disease 2019 (COVID-19) has been recently emphasized. Coronary artery calcium (CAC) score is considered to be a risk predictor of cardiovascular events. Therefore, we have conducted a review of literature on the predictive value of CAC score predictive value in COVID-19 outcome.
METHOD
A search of literature was conducted, aiming for articles published until December 2021 on PubMed and Scopus to identify potentially eligible studies.
DISCUSSION
A total of 18 articles were reviewed for association between higher CAC score and adverse outcomes in COVID-19.
CONCLUSION
The coronary calcium score could be considered as a new radiological marker for risk assessment in COVID-19 patients and providing additional information in fields of prognosis and possible cardiovascular complications. High CAC score is associated with higher in-hospital death and adverse clinical outcomes in patients with confirmed COVID-19, which highlights the importance of calcium load testing for hospitalized COVID-19 patients and calls for attention to patients with high CAC scores.
背景与目的
近期已强调了已知心血管危险因素与2019冠状病毒病（COVID-19）预后不良之间的关联。冠状动脉钙化（CAC）评分被认为是心血管事件的风险预测指标。因此，我们对关于CAC评分在COVID-19预后中的预测价值的文献进行了综述。
方法
进行文献检索，目标是在PubMed和Scopus上检索截至2021年12月发表的文章，以识别潜在符合条件的研究。
讨论
共审查了18篇关于较高CAC评分与COVID-19不良结局之间关联的文章。
结论
冠状动脉钙化评分可被视为COVID-19患者风险评估的一种新的影像学标志物，并在预后和可能的心血管并发症领域提供额外信息。高CAC评分与确诊COVID-19患者的院内死亡及不良临床结局相关，这凸显了对住院COVID-19患者进行钙负荷检测的重要性，并呼吁关注高CAC评分患者。
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