Pang Raina D, Chai Stephanie H, Tucker Chyna J, Weinberger Andrea H, D'Orazio Lina M, Kirkpatrick Matthew G
Department of Population and Public Health Sciences, University of Southern California, United States of America; Department of Psychology, University of Southern California, United States of America.
Department of Population and Public Health Sciences, University of Southern California, United States of America; Herman Ostrow School of Dentistry, University of Southern California, United States of America.
J Affect Disord. 2022 Jun 15;307:163-170. doi: 10.1016/j.jad.2022.03.052. Epub 2022 Mar 24.
High negative affect and low positive affect are key depression-related states that may be greater following acute tobacco abstinence. This study aimed to test associations between depression symptom levels and acute tobacco abstinence with negative affect and positive affect.
Following a baseline session, participants attended two counterbalanced laboratory sessions (non-abstinent, abstinent) and completed measures of positive and negative affect at rest (i.e., when not completing a task) and during a film clip task.
Individuals with elevated depression symptoms had higher negative affect and lower positive affect at rest and during the film clip task compared to individuals with low depression symptoms. There was no interaction of depression symptom levels and abstinence on negative and positive affect at rest. There was an interaction of depression symptom level and abstinence on negative and positive affect during the film clip task. Individuals with elevated depression showed significant differences in positive and negative affect between the abstinent and non-abstinent session, but no significant abstinence effects were noted in individuals with low depression symptoms.
The study included a non-treatment seeking sample and experimentally induced acute cigarette abstinence. We excluded for the use of smoking cessation medications that are also used to treat depression, classified depression levels using dichotomized CES-D scores, and used self-report measures of affect.
Results of this study suggest individuals with elevated depression symptoms who smoke experience elevated negative affect and lower positive affect and cigarette abstinence may uniquely alter affective reactivity in individuals with elevated depression symptoms.
高负性情绪和低正性情绪是与抑郁症相关的关键状态，在急性戒烟后可能会更严重。本研究旨在测试抑郁症状水平和急性戒烟与负性情绪和正性情绪之间的关联。
在基线期之后，参与者参加了两个平衡的实验室环节（非戒烟、戒烟），并在静息状态（即不完成任务时）和观看电影片段任务期间完成了正负性情绪测量。
与抑郁症状较轻的个体相比，抑郁症状较重的个体在静息状态和观看电影片段任务期间具有更高的负性情绪和更低的正性情绪。在静息状态下，抑郁症状水平和戒烟对正负性情绪没有交互作用。在观看电影片段任务期间，抑郁症状水平和戒烟对正负性情绪存在交互作用。抑郁症状较重的个体在戒烟和非戒烟环节之间的正负性情绪存在显著差异，但抑郁症状较轻的个体未观察到明显的戒烟效应。
本研究纳入了一个未寻求治疗的样本，并通过实验诱导急性戒烟。我们排除了使用也用于治疗抑郁症的戒烟药物，使用二分法的CES-D分数对抑郁水平进行分类，并使用自我报告的情绪测量方法。
本研究结果表明，吸烟的抑郁症状较重的个体经历更高的负性情绪和更低的正性情绪，戒烟可能会独特地改变抑郁症状较重个体的情绪反应性。
