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综合介入放射学、内镜和药物治疗改善乙型/丙型肝炎病毒相关失代偿期肝硬化。

Drastic Improvement in Hepatitis B/C Virus-induced Decompensated Liver Cirrhosis Treated by Total Management Consisting of Interventional Radiology, Endoscopy, and Pharmacotherapy.

机构信息

Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, Japan.

出版信息

Intern Med. 2022 Nov 1;61(21):3217-3223. doi: 10.2169/internalmedicine.9240-21. Epub 2022 Mar 26.

Abstract

Recent advances in antiviral therapy have enabled control of the hepatitis virus; however, these do not completely eliminate the pathological condition of liver disease, and portal hypertension remains a clinical problem. We herein report a case of hepatitis B virus/hepatitis C virus (HBV/HCV)-induced decompensated liver cirrhosis for which total management consisting of interventional radiology and endoscopy, based on the evidence of our clinical studies, followed by antiviral therapy for co-infection with HBV and HCV was successful. This case clearly indicates the effective timing of total management, suggesting that it prolongs the vital prognosis in addition to improving the hepatic function.

摘要

近年来,抗病毒治疗的进展使得人们能够控制肝炎病毒;然而,这些治疗并不能完全消除肝病的病理状况,门静脉高压仍然是一个临床问题。我们在此报告一例乙型肝炎病毒/丙型肝炎病毒(HBV/HCV)引起的失代偿性肝硬化病例,根据我们的临床研究证据,对该病例进行了包括介入放射学和内镜治疗在内的综合管理,然后对 HBV 和 HCV 合并感染进行抗病毒治疗,取得了成功。该病例清楚地表明了综合管理的有效时机,提示除了改善肝功能外,还能延长患者的生存预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fee1/9683805/2b2dfd09c4ce/1349-7235-61-3217-g001.jpg

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