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[肺移植中的体外膜肺氧合]

[Extracorporeal Membrane Oxygenation in Lung Transplantation].

作者信息

Konoeda Chihiro, Sato Masaaki, Nakajima Jun

机构信息

Department of Thoracic Surgery, The University of Tokyo, Tokyo, Japan.

出版信息

Kyobu Geka. 2022 Apr;75(4):254-258.

Abstract

Multiple situations necessitate extracorporeal membrane oxygenation( ECMO) during lung transplantation. ECMO can also be used as a bridge to lung transplantation. We describe five cases in which bridging ECMO was successfully utilized, including three cases of living donor lung transplantation. ECMO can also be used as an alternative to cardiopulmonary bypass for intraoperative support during lung transplantation, and postoperatively, primary graft dysfunction, rejection, and infection can cause reversible respiratory failure which warrants ECMO. It can also be used for patients with pulmonary arterial hypertension in the early postoperative period to help their hearts adjust to new circulation. Eight patients with pulmonary arterial hypertension who underwent lung transplantation at our institu-tion received intraoperative and early postoperative ECMO support and their postoperative courses were uneventful. In this report, we review the indications for ECMO and the type of ECMO required for each of the various issues that can arise during lung transplantation, based on the literature and our experiences.

摘要

在肺移植过程中,多种情况需要体外膜肺氧合(ECMO)。ECMO也可作为肺移植的桥梁。我们描述了成功使用过渡性ECMO的5例病例,包括3例活体供肺移植。ECMO还可替代体外循环用于肺移植术中的支持,术后,原发性移植肺功能障碍、排斥反应和感染可导致可逆性呼吸衰竭,这需要使用ECMO。它也可用于术后早期患有肺动脉高压的患者,以帮助他们的心脏适应新的循环。在我们机构接受肺移植的8例肺动脉高压患者术中及术后早期接受了ECMO支持,术后过程顺利。在本报告中,我们根据文献和我们的经验,回顾了ECMO的适应证以及肺移植过程中可能出现的各种问题所需的ECMO类型。

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