酒萸肉中的环烯醚萜类成分

[Iridoids of wine-processed Corni Fructus].

作者信息

Li Hong-Bin, Feng Qing-Mei, Zhang Ling-Xia, Wang Jing, Chi Jun, Wang Zhi-Min, Dai Li-Ping, Chen Sui-Qing

机构信息

School of Pharmacy, Henan University of Chinese Medicine Zhengzhou 450046, China Engineering Technology Research Center for Comprehensive Development and Utilization of Authentic Medicinal Materials in Henan Province, Henan University of Chinese Medicine Zhengzhou 450046, China.

Engineering Technology Research Center for Comprehensive Development and Utilization of Authentic Medicinal Materials in Henan Province, Henan University of Chinese Medicine Zhengzhou 450046, China National Engineering Laboratory for Quality Control Technology of Chinese Herbal Medicines, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2022 Mar;47(5):1273-1278. doi: 10.19540/j.cnki.cjcmm.20211109.202.

DOI:10.19540/j.cnki.cjcmm.20211109.202

PMID:35343154

Abstract

A new iridoid glycoside, cornushmf A(1) and nine known iridoids(2-10) were isolated from the water extract of the wine-processed Corni Fructus by various column chromatographies. Their chemical structures were identified by comprehensive spectroscopic methods as 7β-O-(2″-formylfuran-5″-methylene)-morroniside(1), 7-dehydrologanin(2), sweroside(3), 7β-O-methylmorroniside(4), 7α-O-methylmorroniside(5), 7β-O-ethylmorroniside(6), 7α-O-ethylmorroniside(7), cornuside(8), sarracenin(9), and loganin(10).

摘要

通过各种柱色谱法从酒制山茱萸的水提取物中分离得到一种新的环烯醚萜苷，山茱萸苷A（1）和9种已知的环烯醚萜（2 - 10）。通过综合光谱方法确定它们的化学结构分别为7β - O -（2″ - 甲酰基呋喃 - 5″ - 亚甲基） - 莫诺苷（1）、7 - 脱氢马钱苷（2）、獐牙菜苷（3）、7β - O - 甲基莫诺苷（4）、7α - O - 甲基莫诺苷（5）、7β - O - 乙基莫诺苷（6）、7α - O - 乙基莫诺苷（7）、山茱萸苷（8）、瓶子草苷（9）和马钱苷（10）。