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拓扑互锁微环作为DNA拓扑结构和DNA-蛋白质相互作用的探针

Topologically-Interlocked Minicircles as Probes of DNA Topology and DNA-Protein Interactions.

作者信息

Rajendran Arivazhagan, Krishnamurthy Kirankumar, Park Seojeong, Nakata Eiji, Kwon Youngjoo, Morii Takashi

机构信息

Institute of Advanced Energy, Kyoto University, Uji, Kyoto, 611-0011, Japan.

College of Pharmacy, Ewha Womans University, Seoul, 120-750, Republic of Korea.

出版信息

Chemistry. 2022 Apr 19;28(22):e202200839. doi: 10.1002/chem.202200839. Epub 2022 Mar 28.

Abstract

Invited for the cover of this issue are Prof. Takashi Morii and co-workers at Kyoto University and Ewha Womans University. The cover image depicts the graphical design and atomic force microscopic (AFM) images of the synthesized topologically-interlocked DNA catenane and rotaxanes inside a frame-shaped DNA origami. Read the full text of the article at 10.1002/chem.202200108.

摘要

本期的封面人物是京都大学和梨花女子大学的森井隆教授及其同事。封面图片展示了在框架状DNA折纸内部合成的拓扑互锁DNA连环体和轮烷的图形设计及原子力显微镜(AFM)图像。可在10.1002/chem.202200108阅读该文章的全文。

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