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术前心电图对预测血管手术后心肌损伤的预后价值。

Prognostic value of preoperative electrocardiography in predicting myocardial injury after vascular surgery.

作者信息

Studzińska Dorota, Polok Kamil, Rewerska Barbara, Kotynia Maksymilian, Rewerski Piotr, Włudarczyk Anna, Górka Jacek, Kózka Mateusz, Szczeklik Wojciech

机构信息

Department of Vascular Surgery and Angiology, St. John Grande Hospital, Kraków, Poland.

Center for Intensive Care and Perioperative Medicine, Jagiellonian University Medical College, Kraków, Poland.

出版信息

Kardiol Pol. 2022;80(5):553-559. doi: 10.33963/KP.a2022.0085. Epub 2022 Mar 28.

Abstract

BACKGROUND

The current European guidelines recommend that a preoperative electrocardiogram (ECG) should be performed routinely in patients scheduled for high-risk surgery. However, the evidence regarding ECG as a predictor of perioperative cardiac complications is weak.

AIM

To evaluate the association of preoperative ECG with short- and long-term outcomes in patients undergoing high-risk vascular procedures.

METHODS

This was a substudy of the international Vascular events In noncardiac Surgery patIents cohort evaluatioN (VISION) Study and included consecutive patients undergoing vascular procedures in a single tertiary center. In each patient, a preoperative 12-lead ECG was evaluated by two experienced clinicians following the Polish Cardiac Society recommendations. We performed routine perioperative troponin monitoring at five time points (one preoperative and four postoperative measurements) to evaluate whether preoperative ECG abnormalities are associated with myocardial injury after noncardiac surgery (MINS) and 1-year major adverse cardiovascular events (MACE) including cardiac death, myocardial infarction, and stroke.

RESULTS

The study group comprised 348 patients, 80.5% of whom were male and the median age (interquartile range [IQR]) was 65 (59-72) years. The incidence of MINS and 1-year MACE was 18.7% and 14.4%, respectively. Multivariable analysis showed that none of the predefined ECG abnormalities (ST depression, left axis deviation, atrial fibrillation, and bundle branch block) was associated with the incidence of MINS or 1-year MACE.

CONCLUSION

This study confirmed that preoperative ECG abnormalities are frequent in patients undergoing high-risk vascular surgery. However, we did not find evidence supporting the relation between preoperative ECG abnormalities and postoperative adverse cardiac outcomes in high-risk patients.

摘要

背景

当前欧洲指南建议,计划进行高风险手术的患者应常规进行术前心电图(ECG)检查。然而,关于心电图作为围手术期心脏并发症预测指标的证据并不充分。

目的

评估术前心电图与接受高风险血管手术患者的短期和长期预后之间的关联。

方法

这是国际非心脏手术患者血管事件队列评估(VISION)研究的一项子研究,纳入了在单一三级中心连续接受血管手术的患者。每位患者的术前12导联心电图由两名经验丰富的临床医生按照波兰心脏病学会的建议进行评估。我们在五个时间点(一次术前和四次术后测量)进行常规围手术期肌钙蛋白监测,以评估术前心电图异常是否与非心脏手术后心肌损伤(MINS)和1年主要不良心血管事件(MACE)相关,MACE包括心源性死亡、心肌梗死和中风。

结果

研究组包括348例患者,其中80.5%为男性,中位年龄(四分位间距[IQR])为65(59 - 72)岁。MINS和1年MACE的发生率分别为18.7%和14.4%。多变量分析显示,预定义的心电图异常(ST段压低、电轴左偏、心房颤动和束支传导阻滞)均与MINS或1年MACE的发生率无关。

结论

本研究证实,接受高风险血管手术的患者术前心电图异常很常见。然而,我们没有发现证据支持高风险患者术前心电图异常与术后不良心脏预后之间的关系。

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