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Efficacy and safety of high doses of safinamide in advanced Parkinson disease.

作者信息

Rodríguez-Jorge Fernando, Beltrán-Corbellini Álvaro, Chico-García J L, Parra-Díaz Paloma, Baena-Álvarez Belén, Pagonabarraga Javier, Pérez-Torre Paula, Pareés Isabel, López-Sendón J L, Martínez-Castrillo J C, Alonso-Cánovas Araceli

机构信息

Movement Disorders Unit. Neurology Department, University Hospital Ramón y Cajal, Madrid, Spain.

Movement Disorders Unit. Neurology Department, University Hospital Ramón y Cajal, Madrid, Spain.

出版信息

Parkinsonism Relat Disord. 2022 Apr;97:73-74. doi: 10.1016/j.parkreldis.2022.03.010. Epub 2022 Mar 23.

DOI:10.1016/j.parkreldis.2022.03.010
PMID:35344893
Abstract
摘要

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J Comp Eff Res. 2025 Jul;14(7):e240228. doi: 10.57264/cer-2024-0228. Epub 2025 Jun 6.
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Safinamide, an inhibitor of monoamine oxidase, modulates the magnitude, gating, and hysteresis of sodium ion current.沙芬酰胺是一种单胺氧化酶抑制剂，可调节钠离子电流的幅度、门控和滞后。
BMC Pharmacol Toxicol. 2024 Feb 8;25(1):17. doi: 10.1186/s40360-024-00739-5.
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Switching from Rasagiline to Safinamide as an Add-On Therapy Regimen in Patients with Levodopa: A Literature Review.
左旋多巴治疗患者从雷沙吉兰转换为沙芬酰胺作为附加治疗方案的文献综述。
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