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曾被诊断为结痂性脓疱病的利什曼原虫性脓疱病:病例研究

Impetigo Leishmaniasis Previously Diagnosed as Crusty Impetigo: A Case Study.

作者信息

Suarez José, Rios Margarita, Estripeaut Dora, Reina Adelys

机构信息

Tropical Medicine, Gorgas Memorial Institute of Health Studies, Panama, PAN.

Sistema Nacional de Investigadores (SNI) Research, Secretaría Nacional de Ciencia, Tecnología e Innovación (SENACYT), Panama, PAN.

出版信息

Cureus. 2022 Feb 22;14(2):e22492. doi: 10.7759/cureus.22492. eCollection 2022 Feb.

DOI:10.7759/cureus.22492
PMID:35345709
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8942141/
Abstract

Cutaneous leishmaniasis is a zoonotic disease caused by several species of protozoa of the genus . Cutaneous leishmaniasis classically presents as an ulcer with heaped edges, but it can also appear as nodular, scabbed, or plaque-like lesions. Its diagnosis requires confirmatory laboratory tests such as a smear, culture, and polymerase chain reaction. However, atypical presentations represent a diagnostic challenge in Tropical Medicine. For instance, localized cutaneous leishmaniasis (LCL) resembles bacterial and fungal tropical dermatological infections. Atypical presentations require an experienced clinician, epidemiological knowledge, and proper diagnostic tests. We present a case of a 10-year-old male who showed classic impetigo-like symptoms, which did not improve with topical or systemic antibiotic therapy. After a thorough case review, the patient was diagnosed with LCL. Therefore, epidemiological and clinical evaluation is crucial when diagnosing, especially in patients who live or have travelled to leishmaniasis-endemic areas.

摘要

皮肤利什曼病是一种由利什曼原虫属的几种原生动物引起的人畜共患病。皮肤利什曼病典型表现为边缘隆起的溃疡,但也可表现为结节状、结痂状或斑块状病变。其诊断需要进行涂片、培养和聚合酶链反应等确诊性实验室检查。然而,非典型表现给热带医学带来了诊断挑战。例如,局限性皮肤利什曼病(LCL)类似于细菌性和真菌性热带皮肤病感染。非典型表现需要经验丰富的临床医生、流行病学知识和适当的诊断测试。我们报告一例10岁男性病例,该患者表现出典型的脓疱疮样症状,局部或全身抗生素治疗均无改善。经过全面的病例回顾,该患者被诊断为LCL。因此,在诊断时,尤其是对于居住在或前往过利什曼病流行地区的患者,进行流行病学和临床评估至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a65/8942141/cab10146057a/cureus-0014-00000022492-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a65/8942141/1b44e3eb1aea/cureus-0014-00000022492-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a65/8942141/e675fc2c3769/cureus-0014-00000022492-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a65/8942141/cab10146057a/cureus-0014-00000022492-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a65/8942141/1b44e3eb1aea/cureus-0014-00000022492-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a65/8942141/e675fc2c3769/cureus-0014-00000022492-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a65/8942141/cab10146057a/cureus-0014-00000022492-i03.jpg

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引用本文的文献

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本文引用的文献

1
American cutaneous leishmaniasis in infancy and childhood.婴幼儿期美国皮肤利什曼病。
Int J Dermatol. 2017 Dec;56(12):1328-1341. doi: 10.1111/ijd.13664. Epub 2017 Jul 25.
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Three new sensitive and specific heat-shock protein 70 PCRs for global Leishmania species identification.
三种新的敏感和特异热休克蛋白 70 PCR 用于全球利什曼原虫种属鉴定。
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