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巴基斯坦皮肤利什曼病的罕见临床变种。

Unusual clinical variants of cutaneous leishmaniasis in Pakistan.

作者信息

Raja K M, Khan A A, Hameed A, Rahman S B

机构信息

Department of Dermatology, Combined Military Hospital Quetta, Multan Cantt, Pakistan.

出版信息

Br J Dermatol. 1998 Jul;139(1):111-3. doi: 10.1046/j.1365-2133.1998.02325.x.

DOI:10.1046/j.1365-2133.1998.02325.x
PMID:9764160
Abstract

Cutaneous leishmaniasis is endemic in the Baluchistan province of Pakistan and poses a great risk to non-immune visitors to the area. The wide spectrum of clinical variants of this common disease is at times a diagnostic challenge. A total of 1709 patients with cutaneous leishmaniasis were recorded over a 1-year period. In 37 (2%) patients the lesions were very unusual, and therefore worth reporting. These included acute paronychial, chancriform, annular, palmoplantar, zosteriform and erysipeloid forms. The zosteriform and erysipeloid forms have rarely been reported previously, but to the best of our knowledge, acute paronychial, chancriform, annular and palmoplantar lesions are being reported for the first time. The morphologically unusual lesions may be attributed to an altered host response or involvement of an atypical strain of parasite in these lesions.

摘要

皮肤利什曼病在巴基斯坦俾路支省呈地方性流行,对该地区无免疫力的来访者构成巨大风险。这种常见疾病临床变种的广泛范围有时是一项诊断挑战。在1年期间共记录了1709例皮肤利什曼病患者。在37例(2%)患者中,皮损非常不寻常,因此值得报告。这些包括急性甲沟炎样、下疳样、环状、掌跖、带状疱疹样和丹毒样形态。带状疱疹样和丹毒样形态此前鲜有报道,但据我们所知,急性甲沟炎样、下疳样、环状和掌跖皮损是首次报道。形态学上不寻常的皮损可能归因于宿主反应改变或这些皮损中有非典型寄生虫菌株的感染。

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