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急性肾损伤诊断计算器的评估:一项调查和内容分析。

Evaluation of an ARF diagnosis calculator: a survey and content analysis.

机构信息

Division of Medicine, Royal Darwin Hospital, Darwin, NT, Australia.

RHD Australia, Darwin, Australia.

出版信息

BMC Med Inform Decis Mak. 2022 Mar 26;22(1):77. doi: 10.1186/s12911-022-01816-7.

Abstract

BACKGROUND

Acute Rheumatic Fever (ARF) is a critically important condition for which there is no diagnostic test. Diagnosis requires the use of a set of criteria comprising clinical, laboratory, electrocardiographic and echocardiographic findings. The complexity of the algorithm and the fact that clinicians lack familiarity with ARF, make ARF diagnosis ideally suited to an electronic decision support tool. The ARF Diagnosis Calculator was developed to assist clinicians in diagnosing ARF and correctly assign categories of 'possible, 'probable' or 'definite' ARF. This research aimed to evaluate the acceptability, accuracy, and test performance of the ARF Diagnosis Calculator.

METHODS

Three strategies were used to provide triangulation of data. Users of the calculator employed at Top End Health Service, Northern Territory, Australia were invited to participate in an online survey, and clinicians with ARF expertise were invited to participate in semi-structured interviews. Qualitative data were analysed using inductive analysis. Performance of the calculator in correctly diagnosing ARF was assessed using clinical data from 35 patients presenting with suspected ARF. Diagnoses obtained from the calculator were compared using the Kappa statistic with those obtained from a panel of expert clinicians.

RESULTS

Survey responses were available from 23 Top End Health Service medical practitioners, and interview data were available from five expert clinicians. Using a 6-point Likert scale, participants highly recommended the ARF Diagnosis Calculator (median 6, IQR 1), found it easy to use (median 5, IQR 1) and believed the calculator helped them diagnose ARF (median 5, IQR 1). Clinicians with ARF expertise noted that electronic decision making is not a substitute for clinical experience. There was high agreement between the ARF Diagnosis Calculator and the 'gold standard' ARF diagnostic process (κ = 0.767, 95% CI: 0.568-0.967). Incorrect assignment of diagnosis occurred in 4/35 (11%) patients highlighting the greater accuracy of expert clinical input for ambiguous presentations. Sixteen changes were incorporated into a revised version of the calculator.

CONCLUSIONS

The ARF Diagnosis Calculator is an easy-to-use, accessible tool, but it does not replace clinical expertise. The calculator performed well amongst clinicians and is an acceptable tool for use within the clinical setting with a high level of accuracy in comparison to the gold standard diagnostic process. Effective resources to support clinicians are critically important for improving the quality of care of ARF.

摘要

背景

急性风湿热(ARF)是一种非常重要的疾病,目前尚无诊断性检测手段。诊断需要使用一组包含临床、实验室、心电图和超声心动图结果的标准。由于该算法较为复杂,且临床医生对 ARF 认识不足,因此 ARF 的诊断非常适合使用电子决策支持工具。ARF 诊断计算器的开发目的是协助临床医生诊断 ARF 并正确分配“可能”、“可能”或“确定”ARF 的类别。本研究旨在评估 ARF 诊断计算器的可接受性、准确性和测试性能。

方法

采用三种策略对数据进行三角验证。邀请澳大利亚北部地区顶端健康服务机构使用计算器的用户参与在线调查,并邀请具有 ARF 专业知识的临床医生参与半结构化访谈。采用归纳分析法对定性数据进行分析。使用 35 名疑似 ARF 患者的临床数据评估计算器在正确诊断 ARF 方面的性能。使用 Kappa 统计量将计算器获得的诊断结果与一组专家临床医生获得的诊断结果进行比较。

结果

共有 23 名顶端健康服务机构的医生对调查做出了回应,5 名具有 ARF 专业知识的临床医生提供了访谈数据。参与者使用 6 分李克特量表对 ARF 诊断计算器进行了高度评价(中位数为 6,IQR1),认为其易于使用(中位数为 5,IQR1),并认为计算器有助于他们诊断 ARF(中位数为 5,IQR1)。具有 ARF 专业知识的临床医生指出,电子决策并不是临床经验的替代品。ARF 诊断计算器与“金标准”ARF 诊断过程高度一致(κ=0.767,95%CI:0.568-0.967)。在 35 名患者中,有 4 名(11%)患者的诊断分配不正确,这突出表明对于模棱两可的表现,专家临床输入的准确性更高。对计算器进行了 16 项修改。

结论

ARF 诊断计算器易于使用且易于获取,但它不能替代临床专业知识。该计算器在临床医生中表现良好,与金标准诊断过程相比,其准确性较高,是一种可在临床环境中使用的可接受工具。为了提高 ARF 的护理质量,为临床医生提供有效的资源至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0f2/8961951/bd9a4685f32c/12911_2022_1816_Fig1_HTML.jpg

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