The neoAdjuvant Research Group to Evaluate Therapeutics (TARGET), Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Immunotherapy and Novel TargEt Research Across Clinical Teams (INTERACT), Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Nat Med. 2022 Apr;28(4):626-629. doi: 10.1038/s41591-022-01681-x.
Window-of-opportunity trials, during which patients receive short-duration pre-surgical therapies, provide a platform for understanding the therapies’ mechanisms of action, but will require a paradigm shift in trial design, specimen collection and analysis.
机会之窗试验，在此期间患者接受短疗程术前治疗，为了解治疗的作用机制提供了一个平台，但需要在试验设计、标本采集和分析方面进行范式转变。
