Zoukh K
Pathol Biol (Paris). 1986 Jun;34(5 Pt 2):608-10.
Outbreaks of typhoid fever due to multiresistant strains of S. typhi have occurred in some countries. Monitoring of the susceptibility of S. typhi and paratyphi strains to antibiotics, especially those used to treat Salmonella infections, is therefore essential. In this paper, we report the results of our study of strains isolated in Algeria from 1979 through 1984. Studied strains were isolated in our laboratory from stool or blood samples or sent to us for confirmation of the diagnosis. We used agar dilution with IPA 20 medium (Mueller-Hinton medium enriched with tryptophan). 6,178 strains were tested, including 5,940 S. typhi strains (96.15%), 123 S. paratyphi A strains (1.99%) and 115 S. paratyphi B strains (1.86%). No resistance was found among the strains tested, whereas 7 resistant strains had been found between July 1973 and December 1978. These results indicate that resistant strains have not spread. However, as new resistant strains might emerge in the future, continued monitoring is needed.
一些国家曾爆发由多重耐药伤寒杆菌引起的伤寒热。因此，监测伤寒杆菌和副伤寒杆菌对抗生素的敏感性，尤其是用于治疗沙门氏菌感染的抗生素，至关重要。在本文中，我们报告了1979年至1984年在阿尔及利亚分离出的菌株的研究结果。研究菌株是在我们实验室从粪便或血液样本中分离出来的，或者被送到我们这里进行诊断确认。我们使用含IPA 20培养基（富含色氨酸的穆勒-欣顿培养基）的琼脂稀释法。共检测了6178株菌株，其中包括5940株伤寒杆菌（96.15%）、123株甲型副伤寒杆菌（1.99%）和115株乙型副伤寒杆菌（1.86%）。在所检测的菌株中未发现耐药性，而在1973年7月至1978年12月期间曾发现7株耐药菌株。这些结果表明耐药菌株尚未传播。然而，由于未来可能会出现新的耐药菌株，仍需要持续监测。
