Division of Cardiology, Duke University Medical Center, 2301 Erwin Rd, P.O. Box 3845, Durham, NC, 27710, USA.
Duke Clinical Research Institute, Durham, NC, USA.
Curr Hypertens Rep. 2022 Jul;24(7):205-213. doi: 10.1007/s11906-022-01189-2. Epub 2022 Mar 28.
To review the data on hypertensive disorders of pregnancy (HDP) and heart failure (HF) risk.
Hypertensive disorders are the most common medical condition affecting women during pregnancy and are associated with future HF risk, including peripartum cardiomyopathy, pregnancy-associated HF with preserved ejection fraction, and new-onset HF later in life. HF related to HDP can occur during pregnancy and persist long term, as can be the case with peri-partum cardiomyopathy, or can develop years after delivery through mechanisms that have yet to be clearly defined. Unfortunately, the optimal ways to prevent HDP and its associated HF risks are unclear. Guidelines outlining appropriate risk stratification, coordination of postpartum medical care, and prevention of future cardiovascular disease among with HDP are urgently needed in order to decrease the risk of HF.
回顾妊娠高血压疾病(HDP)和心力衰竭(HF)风险的数据。
高血压疾病是最常见的影响女性在怀孕期间的医疗条件,并与未来 HF 风险相关,包括围产期心肌病、射血分数保留的妊娠相关心力衰竭和以后生活中的新发心力衰竭。与 HDP 相关的 HF 可发生在怀孕期间,并长期持续,如围产期心肌病,也可在分娩多年后通过尚未明确的机制发生。不幸的是,预防 HDP 及其相关 HF 风险的最佳方法尚不清楚。迫切需要制定指南,概述适当的风险分层、产后医疗保健的协调以及 HDP 患者未来心血管疾病的预防,以降低 HF 的风险。