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癌症合并心房颤动患者的抗凝治疗管理。

Management of Anticoagulation in Cancer Patients with Atrial Fibrillation.

机构信息

Department of Pulmonary Circulation, Thromboembolic Diseases and Cardiology, Centre of Postgraduate Medical Education, European Health Centre, Otwock, Poland.

Institute of Hematology and Transfusion Medicine, Warsaw, Poland.

出版信息

Isr Med Assoc J. 2022 Mar;24(3):183-185.

Abstract

Atrial fibrillation is becoming an increasingly important problem in cardio-oncology. Specific risk factors for atrial fibrillation occurrence include type of cancer disease and anticancer drugs. Anticoagulation is often abandoned. The CHA2DS2-VASc and CHA2DS2 scores may be important not only in predicting stroke but also in mortality. The role of new direct oral anticoagulants is growing, but they need to be used in a personalized approach depending on the risk of unbeneficial interactions with cancer treatment and the risk of bleeding.

摘要

心房颤动在心血管肿瘤学中变得越来越重要。心房颤动发生的特定危险因素包括癌症类型和抗癌药物。抗凝治疗经常被放弃。CHA2DS2-VASc 和 CHA2DS2 评分不仅对预测中风很重要,而且对死亡率也很重要。新型直接口服抗凝剂的作用正在增强,但需要根据与癌症治疗无益相互作用的风险和出血风险,采用个体化方法使用。

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