Baraboĭ V A, Chebotarev E E
Radiobiologiia. 1986 Sep-Oct;26(5):591-7.
A hypothesis is validated concerning the products of free radical oxidation of lipids and the phenol compounds as a mediator unit of the stress-syndrome. The data are reviewed on activation of peroxidation under the effect of radiation, cytochemical agents, etc., secondarily stimulating the neurohumoral system function of homeostasis regulation. With the emotional-algesic and cold-stresses, the regulatory system stimulation is of primary, reflex, nature, but it secondarily promotes the peroxidation activation. The radiotoxins (of the quinoid and lipid nature) appearing in tissues under the effect of ionizing radiation, are similar in structure and mechanism of action to peroxidation activation products formed under the effect of other stress-agents.
关于脂质自由基氧化产物和作为应激综合征介导单元的酚类化合物的一种假说得到了验证。回顾了在辐射、细胞化学试剂等作用下过氧化反应的激活数据，这些因素继而刺激了内稳态调节的神经体液系统功能。在情绪性疼痛和冷应激情况下，调节系统的刺激是原发性的、反射性的，但它继而促进了过氧化反应的激活。在电离辐射作用下组织中出现的放射毒素（醌类和脂质性质），在结构和作用机制上与其他应激因素作用下形成的过氧化反应激活产物相似。
