局部募集并为细胞动力工厂提供能量以支持细胞侵袭。
Local recruitment and fueling of the cellular powerplant to support cell invasion.
作者信息
Shannon Nathaniel, Cunniff Brian
机构信息
Department of Pathology and Laboratory Medicine, The Robert Larner M.D. College of Medicine, University of Vermont, Burlington, VT 05405, USA; University of Vermont Cancer Center, Burlington, VT 05405, USA.
Department of Pathology and Laboratory Medicine, The Robert Larner M.D. College of Medicine, University of Vermont, Burlington, VT 05405, USA; University of Vermont Cancer Center, Burlington, VT 05405, USA.
出版信息
Dev Cell. 2022 Mar 28;57(6):689-690. doi: 10.1016/j.devcel.2022.03.002.
In this issue of Developmental Cell, Garde et al. demonstrate that polarized expression of the glucose transporter FGT-1, accompanied by a localized glucose gradient and mitochondrial recruitment to the basal membrane of the anchor cell (AC), supports localized ATP generation required for basement membrane (BM) invasion in C. elegans.
在本期《发育细胞》杂志中，加德等人证明，葡萄糖转运蛋白FGT-1的极化表达，伴随着局部葡萄糖梯度以及线粒体向锚定细胞（AC）基底膜的募集，支持了秀丽隐杆线虫中基底膜（BM）入侵所需的局部ATP生成。
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