Moesgaard-Nielsen V, Vinther B, Illum P, Harvig H
Rhinology. 1986 Sep;24(3):175-9.
The effect of fluocortin butylester (FCB) in the topical treatment of perennial rhinitis was investigated in a double-blind study using a cross-over technique. The daily dose was 4 mg. Of the 30 patients who completed the trial, 26 had either allergy or nasal eosinophilia. 20 of the 30 patients preferred FCB to placebo. Moreover, there was a positive, but not statistically significant, therapeutic effect according to the patient score cards (0.1 less than p less than 0.2). In other words, the results are positive, but not definite. It is concluded that possibly the dose ought to be increased to obtain a more reliable effect.
采用交叉技术进行双盲研究，调查了氟轻松丁酯（FCB）局部治疗常年性鼻炎的效果。每日剂量为4毫克。在完成试验的30名患者中，26名有过敏或鼻嗜酸性粒细胞增多。30名患者中有20名更喜欢FCB而不是安慰剂。此外，根据患者评分卡，有积极但无统计学意义的治疗效果（0.1＜p＜0.2）。换句话说，结果是积极的，但不明确。得出的结论是，可能应该增加剂量以获得更可靠的效果。
