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一项关于加拿大医生为2型糖尿病患者开具每周一次司美格鲁肽注射剂的经验及治疗满意度的调查。

A survey of physician experience and treatment satisfaction prescribing once-weekly semaglutide injections for patients with type 2 diabetes in Canada.

作者信息

Qureshy Kamran, Ross Kirk Andreas, Lyng Wolden Michael, Abbas Mohseni Zonoozi Amir, Liu Aiden

机构信息

Complete Endocrine Care, Vaughan, Ontario, Canada.

Novo Nordisk A/S, Søborg, Denmark.

出版信息

Cardiovasc Endocrinol Metab. 2022 Mar 23;11(2):e0260. doi: 10.1097/XCE.0000000000000260. eCollection 2022 Jun.

Abstract

We assessed physicians' experiences of prescribing once-weekly (OW) semaglutide to patients with type 2 diabetes (T2D) in Canada. Physicians who had prescribed OW semaglutide to ≥2 patients with T2D in the past 12 months and had been doing so for ≥3 months were surveyed during 1-17 October 2018. Prescribing reasons, treatment satisfaction and reasons for discontinuation were assessed. Of the 50 participants, 72% and 54% were prescribed OW semaglutide due to its superior glycemic control and effect on weight, respectively. Most physicians were more satisfied with injection frequency (62%), effect on weight (60%), achieving HbA1c target (54%) and therapy simplicity (50%) with OW semaglutide versus other glucagon-like peptide-1 receptor agonists. Treatment discontinuations in 13% of OW semaglutide-treated patients were reported by physicians, primarily due to gastrointestinal symptoms (70%). The survey suggests that physicians are satisfied with the OW semaglutide clinical effects. Video Abstract: http://links.lww.com/CAEN/A34.

摘要

我们评估了加拿大医生为2型糖尿病(T2D)患者开具每周一次(OW)司美格鲁肽的经验。在2018年10月1日至17日期间,对过去12个月内为≥2名T2D患者开具过OW司美格鲁肽且已持续≥3个月的医生进行了调查。评估了开药原因、治疗满意度和停药原因。在50名参与者中,分别有72%和54%的人因OW司美格鲁肽具有更好的血糖控制和体重影响而开具该药。与其他胰高血糖素样肽-1受体激动剂相比,大多数医生对OW司美格鲁肽的注射频率(62%)、对体重的影响(60%)、实现糖化血红蛋白(HbA1c)目标(54%)和治疗简便性(50%)更满意。医生报告称,13%接受OW司美格鲁肽治疗的患者停药,主要原因是胃肠道症状(70%)。该调查表明医生对OW司美格鲁肽的临床效果感到满意。视频摘要:http://links.lww.com/CAEN/A34

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