Qureshy Kamran, Ross Kirk Andreas, Lyng Wolden Michael, Abbas Mohseni Zonoozi Amir, Liu Aiden
Complete Endocrine Care, Vaughan, Ontario, Canada.
Novo Nordisk A/S, Søborg, Denmark.
Cardiovasc Endocrinol Metab. 2022 Mar 23;11(2):e0260. doi: 10.1097/XCE.0000000000000260. eCollection 2022 Jun.
We assessed physicians' experiences of prescribing once-weekly (OW) semaglutide to patients with type 2 diabetes (T2D) in Canada. Physicians who had prescribed OW semaglutide to ≥2 patients with T2D in the past 12 months and had been doing so for ≥3 months were surveyed during 1-17 October 2018. Prescribing reasons, treatment satisfaction and reasons for discontinuation were assessed. Of the 50 participants, 72% and 54% were prescribed OW semaglutide due to its superior glycemic control and effect on weight, respectively. Most physicians were more satisfied with injection frequency (62%), effect on weight (60%), achieving HbA1c target (54%) and therapy simplicity (50%) with OW semaglutide versus other glucagon-like peptide-1 receptor agonists. Treatment discontinuations in 13% of OW semaglutide-treated patients were reported by physicians, primarily due to gastrointestinal symptoms (70%). The survey suggests that physicians are satisfied with the OW semaglutide clinical effects. Video Abstract: http://links.lww.com/CAEN/A34.
我们评估了加拿大医生为2型糖尿病(T2D)患者开具每周一次(OW)司美格鲁肽的经验。在2018年10月1日至17日期间,对过去12个月内为≥2名T2D患者开具过OW司美格鲁肽且已持续≥3个月的医生进行了调查。评估了开药原因、治疗满意度和停药原因。在50名参与者中,分别有72%和54%的人因OW司美格鲁肽具有更好的血糖控制和体重影响而开具该药。与其他胰高血糖素样肽-1受体激动剂相比,大多数医生对OW司美格鲁肽的注射频率(62%)、对体重的影响(60%)、实现糖化血红蛋白(HbA1c)目标(54%)和治疗简便性(50%)更满意。医生报告称,13%接受OW司美格鲁肽治疗的患者停药,主要原因是胃肠道症状(70%)。该调查表明医生对OW司美格鲁肽的临床效果感到满意。视频摘要:http://links.lww.com/CAEN/A34