Department of Radiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave., Cincinnati, OH, 45229, USA.
Department of Radiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Pediatr Radiol. 2022 Jun;52(7):1224-1233. doi: 10.1007/s00247-022-05335-5. Epub 2022 Mar 29.
Pulmonary lymphoproliferative disorders represent an uncommon spectrum of proliferation of lymphoid tissue in the lung parenchyma ranging from benign hyperplasia to malignancy. They tend to occur in certain clinical situations and have typical imaging features that together can be used by the radiologist to suggest these entities as part of the differential diagnosis. We review key clinical, histopathological and computed tomography features of pulmonary lymphoproliferative disorders in children including follicular bronchiolitis, lymphoid interstitial pneumonia, granulomatous-lymphocytic interstitial lung disease, lymphoma and post-transplant lymphoproliferative disorder to familiarize the pediatric radiologist with this group of disorders.
肺淋巴组织增生性疾病代表了肺实质中淋巴组织增生的一种不常见的谱，从良性增生到恶性肿瘤。它们往往发生在某些临床情况下，具有典型的影像学特征，放射科医生可以结合这些特征来提示这些病变作为鉴别诊断的一部分。我们回顾了儿童肺淋巴组织增生性疾病的关键临床、组织病理学和计算机断层扫描特征，包括滤泡性细支气管炎、淋巴间质肺炎、肉芽肿性淋巴细胞性间质性肺病、淋巴瘤和移植后淋巴组织增生性疾病，以使儿科放射科医生熟悉这组疾病。
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