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淋巴细胞间质性肺炎中的弥漫性肺囊肿:高分辨率CT及病理表现

Diffuse lung cysts in lymphoid interstitial pneumonia: high-resolution CT and pathologic findings.

作者信息

Silva C Isabela S, Flint Julia D, Levy Robert D, Müller Nestor L

机构信息

Department of Radiology, Vancouver General Hospital, University of British Columbia 899 West 12th Avenue, Vancouver, BC, Canada.

出版信息

J Thorac Imaging. 2006 Aug;21(3):241-4. doi: 10.1097/01.rti.0000213554.61752.73.

DOI:10.1097/01.rti.0000213554.61752.73
PMID:16915074
Abstract

Lymphoid interstitial pneumonia is part of a spectrum of pulmonary lymphoproliferative disorders that range from benign, small, and airway-centered cellular infiltrates (follicular bronchiolitis, nodular lymphoid hyperplasia) to low-grade malignant lymphoma. Most of the cases occur in patients with underlying autoimmune disease or immunodeficiency. The characteristic high-resolution computed tomography findings consist of diffuse ground-glass opacities, ill-defined centrilobular nodules, bronchovascular thickening, interlobular septal thickening, and scattered thin-walled cysts. The cysts may be seen in up to 80% of the patients and are typically few in number and measure less than 3 cm in diameter. This case illustrates extensive cysts as the predominant high-resolution computed tomography finding of idiopathic lymphoid interstitial pneumonia in a 64-year-old man who underwent unilateral lung transplant. Such extensive cystic disease and lung transplantation treatment has not been previously described.

摘要

淋巴样间质性肺炎是一系列肺淋巴增殖性疾病的一部分,这些疾病范围从良性、小的、以气道为中心的细胞浸润(滤泡性细支气管炎、结节性淋巴样增生)到低度恶性淋巴瘤。大多数病例发生在患有潜在自身免疫性疾病或免疫缺陷的患者中。高分辨率计算机断层扫描的特征性表现包括弥漫性磨玻璃影、边界不清的小叶中心结节、支气管血管增厚、小叶间隔增厚以及散在的薄壁囊肿。囊肿可见于高达80%的患者,通常数量较少,直径小于3厘米。本病例显示,一名64岁接受单侧肺移植的男性,特发性淋巴样间质性肺炎的主要高分辨率计算机断层扫描表现为广泛的囊肿。此前尚未描述过这种广泛的囊性疾病和肺移植治疗情况。

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