Heart Rhythm Management Centre, Universitair Ziekenhuis Brussel, Postgraduate program in Cardiac Electrophysiology and Pacing, European Reference Networks Guard-Heart, Vrije Universiteit Brussel, Brussels, Belgium.
Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy.
Pacing Clin Electrophysiol. 2022 May;45(5):605-611. doi: 10.1111/pace.14495. Epub 2022 Apr 7.
Left atrial posterior wall isolation (LAPWI) is often performed in addition to pulmonary vein isolation (PVI) in the setting of persistent atrial fibrillation (AF) ablation. The aim of this study was to evaluate the feasibility and safety of a new cryoballoon ablation system in achieving PVI + LAPWI isolation.
The study was a prospective, non-randomized, single center study. Forty consecutive patients, undergoing PVI + LAPWI with the novel POLARx™, were compared to 40 consecutive patients who underwent the same procedure with the established Arctic Front Advance PRO™.
Acute isolation was achieved in all PVs in both groups and left posterior wall isolation (LAPWI) was achieved in 38 patients (95%) in the POLARx group and in 36 patients (90%) in Arctic Front group. Procedural outcomes were similar between both groups, except for lower temperatures during cryoenergy in the POLARx group, for both pulmonary vein isolation (PVI) and LAPWI.
LAPWI + PVI with the novel POLARx™ Cryoballoon is feasible and safe; the results are comparable with the Arctic Front Advance PRO™ system.
在持续性房颤消融治疗中，左心房后壁隔离（LAPWI）通常与肺静脉隔离（PVI）联合进行。本研究旨在评估新型冷冻球囊消融系统在实现 PVI+LAPWI 隔离中的可行性和安全性。
该研究为前瞻性、非随机、单中心研究。40 例连续患者接受新型 POLARx™行 PVI+LAPWI 治疗，与 40 例接受 Arctic Front Advance PRO™行相同手术的连续患者进行比较。
两组患者均成功实现所有肺静脉的即刻隔离，38 例（95%）POLARx 组和 36 例（90%）Arctic Front 组实现左后壁隔离（LAPWI）。除了在 POLARx 组的 PVI 和 LAPWI 中冷冻能量的温度较低外，两组的手术结果相似。
新型 POLARx™冷冻球囊进行 LAPWI+PVI 是可行且安全的；结果与 Arctic Front Advance PRO™系统相当。
